Yigit, BeyhanGok, YetkinOzdemir, IlknurGunal, Selami2024-08-042024-08-0420120095-89721029-0389https://doi.org/10.1080/00958972.2012.654469https://hdl.handle.net/11616/104235The synthesis and antimicrobial studies of 1-methyl-2-dimethylaminoethyl-substituted carbene precursors and silver complexes are reported. The carbene precursors (1a-d) have been prepared from 1-methyl-2-dimethylaminoethyl-substituted benzimidazole and various alkyl halides. The silver-NHC complexes (2a-d) were synthesized from the benzimidazolium salts and Ag2O in dichloromethane at room temperature. The new compounds were characterized by H-1 NMR, C-13 NMR, FT-IR, and elemental analyses. The new carbene precursors and Ag-complexes were tested for their in vitro antimicrobial activity against a variety of Gram-positive and Gram-negative bacteria, as well as for their antifungal activities against Candida albicans and Candida tropicalis.eninfo:eu-repo/semantics/closedAccessN-heterocyclic carbeneBenzimidazolium saltsSilverAntimicrobialMedical inorganic chemistrySynthesis and antimicrobial studies of 1-methyl-2-dimethylaminoethyl-substituted benzimidazolium salts and N-heterocyclic carbene-silver complexesArticle65337137910.1080/00958972.2012.654469WOS:000302035700001Q2