Ateş, MustafaDirican, Abuzerİnce, VolkanAra, CengizIşık, BurakYılmaz, Sezai2017-08-082017-08-082012Ateş, M. Dirican, A. İnce, V. Ara, C. Işık, B. Yılmaz, S. (2012). Comparison of intracorporeal knot tying suture polyglactin and titanium endoclips in laparoscopic appendiceal stump closure. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, 22(3), 226–231.1530-4515http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00129689-201206000-00012https://hdl.handle.net/11616/7487Background: Laparoscopic appendectomy is a well-described surgical technique. However, concerns still exist regarding whether the closure of the appendiceal stump should be done with a clip, an endoloop, staples, or other techniques. Therefore, several modifications to the original technique with new materials have been introduced for appendiceal stump closure. The aim of this study was to compare intracorporeal (polyglactin) knot-tying suture with titanium endoclips in appendiceal stump closure during laparoscopic appendectomy. Methods: The study was carried out as a prospective randomized clinical trial between April 2010 and February 2011. Patients with a presentation of appendicitis were included into the study. Two groups were defined—patients with the titanium endoclip and patients with the knot-tying (polyglactin) suture. The results in terms of operating time, complication rates, and hospital stay were analyzed. Results: Sixty-one patients who underwent laparoscopic appendectomy were enrolled in the titanium endoclip group (n= 30) or the knot-tying (polyglactin) suture group (n= 31). No statistically significant differences were detected between the groups in terms of the distribution of age, sex percentage, appendix localization, and histopathologic diagnosis (P> 0.05). One patient required a second operation on postoperative day 10 because of intraperitoneal abscess. The mean operative time for the endoclip group (41.27± 12.2 min) was shorter than that for the knot-tying group (62.81± 15.4 min) (P= 0.001). No statistically significant differences were detected between the groups in terms of hospital stay, follow-up time, and preoperative and postoperative complications (P> 0.05). Conclusions: In laparoscopic appendectomy, using a titanium endoclip for optimizing and controlling the appendiceal stump closure is safe and is associated with shorter operation time. This also simplifies the procedure, so it can be a useful alternative to intracorporeal knot-tying for appendiceal stump closure.eninfo:eu-repo/semantics/openAccessLaparoscopyAppendectomyKnot-tyingEndoclipArticle22322623110.1097/SLE.0b013e31824f25cd