Kaloglu, MuratKaloglu, NazanOzdemir, IlknurGunal, SelamiOzdemir, Ismail2024-08-042024-08-0420160968-08961464-3391https://doi.org/10.1016/j.bmc.2016.06.004https://hdl.handle.net/11616/97410Novel benzimidazolium salts were synthesized as N-heterocyclic carbene (NHC) precursors, these NHC precursors were metallated with Ag2O in dichloromethane at room temperature to give novel silver (I)-NHC complexes. Structures of these benzimidazolium salts and silver(I)-NHC complexes were characterized on the basis of elemental analysis, H-1 NMR, C-13 NMR, IR and LC-MS spectroscopic techniques. A series of benzimidazolium salts and silver(I)-NHC complexes were tested against standard bacterial strains: Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and the fungal strains: Candida albicans and Candida tropicalis. The results showed that benzimidazolium salts inhibited the growth of all bacteria and fungi strains and all silver(I)-NHC complexes performed good activities against different microorganisms. (C) 2016 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessN-Heterocyclic carbeneSilver(I)-NHC complexesBenzimidazolium saltsMetallopharmaceuticals in vitroantimicrobial activityArticle2416364936562730168010.1016/j.bmc.2016.06.0042-s2.0-84978245394Q2WOS:000380515700036Q2