Karatas, Mert OlgunAlici, BulentCetinkaya, EnginBilen, CigdemGencer, NahitArslan, Oktay2024-08-042024-08-0420141068-16201608-330Xhttps://doi.org/10.1134/S1068162014040049https://hdl.handle.net/11616/965271-Alkylbenzimidazole and 1,3-dialkyl benzimidazolium salts were synthesized and characterized by the data of IR, H-1 NMR, C-13 NMR spectra and elemental analyses. These compounds were investigated as tyrosinase inhibitors. Tyrosinase has been purified from banana by affinity chromatography on a Sepharose 4B gel conjugated with L-tyrosine-p-aminobenzoic acid. All the synthesized compounds inhibited the tyrosinase activity. Among the compounds studied, 1,4-di(1H-benzo[d]imidazol-1-yl)butane was found to be the most active tyrosinase inhibitor (IC50 0.31 mM).eninfo:eu-repo/semantics/closedAccessbenzimidazoleenzymatic browningtyrosinase inhibitorsArticle40446146610.1134/S10681620140400492-s2.0-84905166327Q4WOS:000339925100013Q4