Palladium N-heterocyclic-carbene-catalyzed ortho-arylation of benzaldehyde derivatives

Dogan, OznurGurbuz, NevinOzdemir, IsmailCetinkaya, Bekir2024-08-042024-08-0420081042-71631098-1071https://doi.org/10.1002/hc.20479https://hdl.handle.net/11616/94656New, sterically demanding 1,3-dialkylbenzimidazolium salts (2a-c) as N-heterocyclic-carbene precursors have been synthesized and characterized. The ortho position of aromatic aldehydes was directly and selectively arylated with aryl chlorides in the presence of a catalytic system prepared in situ from Pd(OAc)(2), 1,3-dialkylbenzimidazolium chlorides (2a-c), and Cs2CO3. (C) 2008 Wiley Periodicals, Inc.eninfo:eu-repo/semantics/openAccessCross-Coupling ReactionsC-H BondsMultiple ArylationAryl ChloridesCarbonyl-CompoundsComplexesAlkylationActivationReactivityBromidesPalladium N-heterocyclic-carbene-catalyzed ortho-arylation of benzaldehyde derivativesArticle19656957410.1002/hc.204792-s2.0-52749097281Q4WOS:000259280600004Q3