Şimşek, Ömer YavuzIşık, BurakKaraer, AbdullahÇelik, ÖnderKutlu, RamazanAydın, Nasuhi EnginYılmaz, Sezai2017-08-082017-08-082012Şimşek, Ö. Y. Işık, B. Karaer, A. Çelik, Ö. Kutlu, R. Aydın, N. E. Yılmaz, S. (2012). Fulminant hepatitis A infection in second trimester of pregnancy requiring living donor liver transplantation. Journal of Obstetrics and Gynaecology Research. 4: 745–748.13418076https://hdl.handle.net/11616/7491We present an 18-year-old pregnant woman who was referred to our emergency clinic as a case of acute hepatic failure and hepatic encephalopathy. Laboratory tests showed abnormal liver function tests and serological workup was consistent with acute hepatitis A infection. Ultrasonography revealed a single live fetus with fetal biometry compatible with 18 gestational weeks. The patient underwent a highly urgent liver transplantation using a right lobe graft from her husband. Histological examination of the explanted liver showed acute, lymphocyte-rich, diffuse necrotizing hepatitis, consistent with acute necrotizing hepatitis A. After the operation her allograft function gradually recovered. Her follow-up obstetrics ultrasound revealed a male fetus with severely decreased amniotic fluid. The patient was informed about the poor prognosis of her pregnancy and the pregnancy was terminated by vaginal misoprostol induction. She has maintained a good general condition and liver function for 4 months postoperatively, up to the present time.eninfo:eu-repo/semantics/openAccessHepatic encephalopathyHepatic failureHepatitis ALiver transplantationPregnancyFulminant hepatitis A infection in second trimester of pregnancy requiring living donor liver transplantationArticle474574810.1111/j.1447-0756.2011.01757.x