Synthesis of Quinoxaline-Linked Bis(Benzimidazolium) Salts and Their Catalytic Application in Palladium-Catalyzed Direct Arylation of Heteroarenes

Kaloglu, MuratSahan, Mehmet HanifiDusunceli, Serpil DemirOzdemir, Ismail2024-08-042024-08-0420221011-372X1572-879Xhttps://doi.org/10.1007/s10562-021-03787-2https://hdl.handle.net/11616/100197In this study, quinoxaline-linked bis(benzimidazolium) salts were synthesized as bis-N-heterocyclic carbene (NHC) precursors. These bis(NHC) precursors were used as multidentate ligands for the construction of bi(hetero)aryls by palladium-catalyzed direct C-H activation process. The in situ prepared palladium complexes by mixtures of the Pd(OAc)(2) and the bis(NHC) precursors were used as the catalyst for direct C-H activation of heteroarenes. These catalytic system exhibited a modest catalytic activity in the direct C-H activation of five-membered heteroarenes with a wide range of (hetero)aryl bromides.eninfo:eu-repo/semantics/closedAccessN-Heterocyclic carbeneQuinoxalineMultidentate ligandPalladiumCatalysisDirect arylationHeteroareneSynthesis of Quinoxaline-Linked Bis(Benzimidazolium) Salts and Their Catalytic Application in Palladium-Catalyzed Direct Arylation of HeteroarenesArticle15272012202410.1007/s10562-021-03787-22-s2.0-85114614202Q2WOS:000694558000003Q3