Onur, AsimAkbulut, SamiDirican, AbuzerIsik, BurakYilmaz, Sezai2024-08-042024-08-0420180902-00631399-0012https://doi.org/10.1111/ctr.13262https://hdl.handle.net/11616/98281ObjectiveTo determine the relationship between a transplant center's experience and life-threatening or nearly life-threatening complications during living donor hepatectomy (LDH). MethodsThe medical records of 1140 patients who underwent LDH were analyzed. To determine the relationship between life-threatening complications and a transplant center's experience, the following comparisons between LDH cases were performed: first 100 vs subsequent 100; first 100 vs subsequent 1040; first 200 vs subsequent 940; right hepatectomy vs left hepatectomy; and first 5years of experience vs subsequent 5years. ResultsA total of 36 life-threatening or nearly life-threatening complications developed in 34 of 1140 (2.98%) healthy individuals undergoing LDH. Of these, 5 occurred intraoperatively, 26 within 1month, and 5 beyond 1month. The most common complications were biliary problems and postoperative bleeding. None of the donors died at follow-up. One donor underwent deceased donor liver transplantation (DDLT) for severe hepatic failure. Only 2 comparisons were significantly different with regard to life-threatening complications: the first 100 vs the subsequent 1040 (P=.03) and the first 200 vs the subsequent 940 (P=.01). ConclusionThis study indicates that the incidence of life-threatening or nearly life-threatening complications are reduced by increased center experience (>200 LDHs).eninfo:eu-repo/semantics/closedAccessintraoperative complicationslife-threatening complicationsliving donor hepatectomynearly life-threatening complicationspostoperative complicationsArticle3262966507610.1111/ctr.132622-s2.0-85046773050Q1WOS:000436538300009Q3