Aktas, AydinErdemir, FatosCelepci, Duygu BarutGok, YetkinAygun, Muhittin2024-08-042024-08-0420190340-42851572-901Xhttps://doi.org/10.1007/s11243-018-0286-5https://hdl.handle.net/11616/98531A series of 2-hydroxyethyl-substituted N-heterocyclic carbene-(NHC)PdX2PPh3 complexes have been synthesized by substitution of the pyridine or 3-chloropyridine ligand in (NHC)PdX2(pyridine/3-chloropyridine) complexes with triphenylphosphine. The new complexes were characterized by H-1, C-13 {H-1}, P-31 {H-1}NMR, FTIR spectroscopy and elemental analysis. Also, the molecular and crystal structures of 1c and 1d have been obtained by single-crystal X-ray diffraction. The 2-hydroxyethyl-substituted (NHC)PdX2PPh3 complexes have been examined as catalysts for the Sonogashira cross-coupling reaction in water/DMF solvent mixtures.eninfo:eu-repo/semantics/closedAccessCoupling ReactionSuzuki-MiyauraAryl ChloridesCopper FreeLigandsCatalystsEfficientMixed phosphine/N-heterocyclic carbene-palladium complexes: synthesis, characterization, crystal structure and application in the Sonogashira reaction in aqueous mediaArticle44322923610.1007/s11243-018-0286-52-s2.0-85056251393Q2WOS:000463677600003Q3