Access to 3-methyl-4-methylene-N-tosylpyrrolidine and 3,4-dimethyl-N-tosylpyrroline by ruthenium-catalyzed cascade cycloisomerization/isomerization reactions

Özdemir, IÇetinkaya, EÇetinkaya, BÇicek, MSémeril, DBruneau, CDixneuf, PH2024-08-042024-08-0420041434-19481099-0682https://doi.org/10.1002/ejic.200300224https://hdl.handle.net/11616/93734New RuCl2(benzimidazole)(arene) complexes have been prepared. Upon reaction with 1,1-diphenylprop-2-ynol they generate catalyst precursors which perform the cycloisomerization of diallyltosylamide into 3-methyl-4-methylene-N-tosylpyrrolidine. The presence of N-(2,4,6-trimethyl-benzyl)benzimidazole as ligand leads to a subsequent isomerization and gives the 3,4-dimethyl-N-tosylpyrroline. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.eninfo:eu-repo/semantics/closedAccessrutheniumbenzimidazolehomogeneous catalysisolefinationAccess to 3-methyl-4-methylene-N-tosylpyrrolidine and 3,4-dimethyl-N-tosylpyrroline by ruthenium-catalyzed cascade cycloisomerization/isomerization reactionsArticle241842210.1002/ejic.2003002242-s2.0-0742288606Q2WOS:000188711900028Q2