Hargura, Abdirahman SakulenElsarawy, AhmedAkbulut, Sami2026-04-042026-04-042025978-303197277-5978-303197276-8https://doi.org/10.1007/978-3-031-97277-5_3https://hdl.handle.net/11616/107980Echinococcal infestation is an important health problem that needs vigilant screening and stepwise approach for diagnosis, treatment, and follow up as dictated by the World Health Organization (WHO). The most common forms are cystic echinococcosis caused by Echinococcus granulosus and alveolar echinococcosis caused by Echinococcus multilocularis. Liver hydatid disease is increasingly encountered worldwide with the rise in health awareness and availability of medical diagnostics, in addition to the active immigration across the globe. Although hydatid disease (especially cystic echinococcosis) is most commonly seen in the liver and lungs, it can affect many tissues and organs in the body. In hydatid cyst involvement of almost all organs, patients remain asymptomatic for varying periods and diagnosed with an incidental radiological finding done on routine examination. In this study, we will summarize the clinical sign and symptoms of hydatid disease, which involves both hepatic and extrahepatic involvement such as lungs, spleen, heart, pancreas, central nervous system, musculoskeletal and soft tissues, kidney and retroperitoneum, subcutaneous tissue, orbital and ocular space, head, neck, thyroid and parotid glands. © 2025 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG.eninfo:eu-repo/semantics/closedAccessCentral nervous systemEchinococcosisHeadHeartKidney and retroperitoneumLiverLungsMusculoskeletal and soft tissuesNeckOrbital and ocular spacePancreasParotid glandsSpleenSubcutaneous tissueThyroidBook Part414910.1007/978-3-031-97277-5_32-s2.0-105023597133N/A