Turtay, Muhammet GokhanCiftci, OsmanCetin, AsliGurbuz, SukruOguzturk, HakanBasak, NeseFirat, Cemal2024-08-042024-08-0420210393-63842283-9720https://doi.org/10.19193/0393-6384_2021_2_169https://hdl.handle.net/11616/99898Introduction: This study aims to investigate the effects of chrysin on burn healing in burned model rats. Materials and methods: Rats were burned and randomly divided into four groups. Group 1; the group whose burn wound was left to secondary healing. Group 2; the group to which bacitracin neomycin sulfate pomade was topically administered. Group 3; the group to which chrysin was administered topically and with gastric gavage. Group 4; the group was assigned as the group to which chrysin and bacitracin neomycin sulfate was administered. Results: On days 3, 7 and 14, blood samples and skin biopsies were taken. Necrosis, congestion, hemorrhage and IL-1 beta were found to have the lowest levels on all days when bacitracin and chrysin were administered together. This group was also found to have the lowest level of TNF-alpha serum levels on days 7 and 14. Conclusion: We conclude that chrysin is effective in the treatment of burn wounds when used separately, but when combined with topical bacitracin pomade application, it is more effective for healing.eninfo:eu-repo/semantics/closedAccessChrysinBacitracinBurnRatArticle3721101110710.19193/0393-6384_2021_2_1692-s2.0-85104760491N/AWOS:000640492300054Q4