Kahraman, Aysegul SagirKahraman, BayramOzdemir, Zeynep MarasGormeli, Cemile AyseOzdemir, FatihDogan, Metin2024-08-042024-08-0420162366-004X2366-0058https://doi.org/10.1007/s00261-015-0613-7https://hdl.handle.net/11616/97243Purpose: The aim of this study was to determine the correlation between the liver and spleen apparent diffusion coefficient (ADC) values of patients with chronic liver disease and the presence and the degree of ascites. Materials and method: In this retrospective study, we assessed 107 patients with chronic liver disease and 39 control subjects who underwent upper abdominal MR imaging including echo-planar diffusion-weighted imaging (DWI). Among the 107 cirrhotic patients, 56 were classified as group 1, 25 as group 2, and 26 as group 3 according to the absence, the presence of minimal, and the presence of massive ascites, respectively. The scores of model for end-stage liver disease (MELD) were matched between groups as the standard reference. The liver ADC, spleen ADC, and normalized liver ADC values were compared between the control group and patients' groups. Results: Patients with massive ascites had significantly higher MELD score compared with the other groups. The MELD score was also significantly higher in patient groups than in control group. The liver and normalized liver ADCs of patients' groups were significantly lower than that of the control group. With some overlap among groups, the measured ADC values decreased as the amount of the ascites increased, and these relationships were statistically significant. Furthermore, compared to control group, patients with massive ascites had significantly higher spleen ADCs. Conclusion: Our results indicate that the ADC value of the liver and spleen correlates with the presence and the degree of ascites in patients with chronic liver disease, and merits further study.eninfo:eu-repo/semantics/closedAccessMagnetic resonance imagingDiffusion-weighted MRIADC measurementsChronic liver diseaseAscitesArticle41156622683061210.1007/s00261-015-0613-72-s2.0-84962173336Q1WOS:000374109400009Q4