Köro?lu A.Çiçek M.But A.K.Toprak H.I.Ersoy M.Ö.2024-08-042024-08-0420051300-0578https://hdl.handle.net/11616/91145In this study, it was aimed to evaluate the effects of prilocaine-lidocaine cream applied at different durations on the quality analgesia and procedure and to compare them with those of prilocaine HCI infiltration for internal jugular venous (IJV) cannulation. Seventy-five cases performing IJV cannulation before operations were included in the study. Prilocaine-lidocaine cream was applied before IJV cannulation in Groups I, II, III, and IV during 60, 90, 120 and 180 min, respectively. Prilocaine HCI infiltration was applied in cases of Group V. The level of pain was evaluated with the visual analogue scale during infiltration of prilocaine HCI and IJV cannulation. In addition, the depth of skin-İJV, the quality of analgesia and procedure were recorded. Adequate skin analgesia was obtained in all cases. Number of cases obtained adequate analgesia at different depths in cases in which prilocaine-lidocaine cream was applied were higher in Groups III and IV than in Groups I and II at 0.5 cm depth, higher in Group IV than in Groups I and II, and in Group III than in Group I at 1 cm depth, and higher in Group IV than in Group I at 1.5 cm depth. The quality of analgesia was better in group IV than in Groups I and II. Total number of cases obtained adequate analgesia was significantly higher, the requirement of additional 2% prilokain HCI infiltration was lower in Group IV than in Groups I and II, and also in Group V than in Groups I, II, and III, during IJV cannulation. As a result, we hold the opinion that prilocaine-lidocaine cream applied for 3 h provided more effective analgesia than the shorter duration of application. Also, since when it was applied during 90, 120, and 180 min it provided clinically better the quality of procedure it could be a better alternative to the prilocaine HCI infiltration.trinfo:eu-repo/semantics/closedAccessInternal jugular venous cannulationPrilocaine HCIPrilocaine-lidocaine creamArticle1331941982-s2.0-26944432999Q4