Yildirim M.Gul S.C.Angin Y.S.Saglam A.I.Ozsoy U.Koca B.Ozkan N.2024-08-042024-08-0420240009-7411https://doi.org/10.24875/CIRU.22000529https://hdl.handle.net/11616/90369Objective: The purpose of this study was to research the neutrophil-lymphocyte ratio (NLR), lymphocyte-to-C-reactive protein ratio (LCR), and Fournier's Gangrene Severity Index (FGSI) for predicting prognosis and mortality in patients with Fournier's gangrene (FG). Material and Methods: Patients diagnosed with FG and treated in a tertiary referral hospital in the period from January 2013 to June 2020 were reviewed. LCR, FGSI, and NLR values were calculated. Results: Our series included a total of 41 patients. Of the patients, 78% survived and 21.9% (n = 9) died. Survivors were significantly younger than non-survivors (p = 0.009). Hospital costs were higher in non-survivors and close to statistical significance (p = 0.08). The ROC analysis revealed that the FGSI, LCR, and NLR parameters were significant in identifying survivors and non-survivors (AUC = 0.941 [0.870-1.000], p < 0.001; AUC = 0.747 [0.593-0.900], p = 0.025; and AUC = 0.724 [0.548-0.900], p = 0.042). Conclusion: A low LCR value can be used as a marker to assess mortality and disease severity in patients with Fournier's gangrene. © 2024 Permanyer Publications. All rights reserved.eninfo:eu-repo/semantics/openAccessCost effectiveFournier's gangreneLymphocyte C-reactive protein ratioMortalityLymphocyte-to-C-reactive protein ratio as a new biomarker for predicting mortality and morbidity in Fournier's gangreneArticle9221811883878237410.24875/CIRU.220005292-s2.0-85194130542Q4