Temelli, OztunDemirtas, MehmetUgurlu, Berat Tugrul2024-08-042024-08-0420211460-39691467-1131https://doi.org/10.1017/S1460396920000357https://hdl.handle.net/11616/99316Aim: The purpose of the present study is to compare hybrid [three-dimensional conformal radiation therapy-volumetric-modulated arc therapy (3DCRT-VMAT)] and helical tomotherapy (HT) techniques in terms of both planning target volume (PTV) and organs at risk (OARs) in the plans we made in locally advanced non-small cell lung cancer (NSCLC) patients Material and methods: Radiotherapy was planned for 15 locally advanced NSCLC patients with 2 different techniques. Large tumours with positive mediastinal lymph nodes were preferred. The prescription dose was determined as 60 Gy at 30 fractions. Results: Mean PTV volume was 602 center dot 5 cc (range: 265-1461). Mean total lung volume was 4264 cc (range: 1885-6803). Homogeneity index, D-mean, D-max, D-2 and V-105 were found to be lower in HT, V-100, total monitor units (MU) and total beam on time were found to be lower in the hybrid plan. Total lung D-mean was found to be 17 Gy in both techniques. V-10 value was 42 center dot 85 in the hybrid plan and 48 center dot 67 in HT (p = 0 center dot 037). Heart D-mean was 14 center dot 5 Gy in the hybrid plan and 18 center dot 7 in HT (p < 0 center dot 001), and V-30 values were 18 center dot 1 and 22 center dot 9, respectively (p = 0 center dot 009). Conclusion: Suitable dose coverage and OAR doses can be provided with both techniques. Especially the opposite lung, heart and oesophagus doses can be kept lower with the hybrid plan, and lower MU and shorter beam on time can be provided.eninfo:eu-repo/semantics/closedAccesslung cancerhybrid techniquehelical tomotherapydosimetric comparisonArticle20330030510.1017/S14603969200003572-s2.0-85085565869Q4WOS:000685641200009N/A