Bensalah, DoniaMansour, LamjedSauthier, MathieuGurbuz, NevinOzdemir, IsmailKoko, Waleed S.Gatri, Rafik2024-08-042024-08-0420231144-05461369-9261https://doi.org/10.1039/d3nj04209jhttps://hdl.handle.net/11616/101648The growing interest of industry in the field of bi(hetero)arene compounds motivated us to synthesize these compounds via a homogeneous catalytic route using Pd PEPPSI-type complexes through direct arylation. In this study, new Pd PEPPSI-type complexes bearing NHC spectator ligands were synthesized and characterized using spectroscopic techniques, such as (HNMR)-H-1, C-13 NMR, MS spectrometry, FTIR spectroscopy and elemental analysis (PEPPSI = pyridine enhanced precatalyst preparation stabilization and initiation). All the synthesized Pd(II) complexes were stable. The catalytic properties of these complexes were evaluated in the direct C-5 mono-arylation of furan, 2-acetylthiophene and N-methylpyrrole-2-carboxaldehyde derivatives with a wide variety of (hetero)aryl halides. This environmentally attractive procedure was found to be tolerant of a wide variety of functional groups on the aryl halides and good yields were obtained in the presence of 1 mol% catalyst loading at 150 degrees C for 2 hours. In addition, the conversions for substrates containing electron-withdrawing groups were higher than those for substituents containing electron-donating groups.eninfo:eu-repo/semantics/closedAccessCross-Coupling ReactionPalladium ComplexesBond ArylationHeterogeneous CatalysisPeppsi ComplexesMetal-ComplexesFunctionalizationPrecatalystsActivationRutheniumArticle4744204352045510.1039/d3nj04209j2-s2.0-85175550771Q2WOS:001093937600001Q2