Tetik, Burcu Kayhan, AdemKorkmaz, YavuzBeler, Mehmet2026-04-042026-04-0420252147-0634https://doi.org/10.5455/medscience.2025.06.152https://search.trdizin.gov.tr/tr/yayin/detay/1369787https://hdl.handle.net/11616/107294Telemedicine is a key component in improving healthcare delivery and accessibility, especially when distance poses a challenge. With the increasing digitalization of healthcare, this study aimed to investigate the relationship between e-health literacy and attitudes towards telehealth services. This cross-sectional study included 385 patients aged 45–65 who applied to a family medicine outpatient clinic at a tertiary care center. Participants completed the E-Health Literacy Scale (e-HLS) and the Attitude Scale for the Use of Telemedicine Services (ASUTS). The mean age was 52.67±6.39 years; 86.5% owned mobile phones with internet access, and 66.2% used the E-Nabız application. In case of a health problem, the Family Health Center was the most frequently visited institution (49.6%), followed by State Hospitals (23.9%). A moderately positive correlation was observed between e-health literacy and attitudes towards telehealth services (r=0.485, p<0.001). Multivariable linear regression showed that each one-unit increase in e-health literacy was associated with a 0.956-unit increase in attitude scores (p<0.001). Higher attitude scores were found among males, individuals over 50, those with education above high school, E-Nabız users, and participants who considered the internet useful and important (p<0.05). The findings suggest that improving e-health literacy may positively influence acceptance of telehealth services. This can be achieved by enhancing access to digital health platforms, developing user-friendly technologies, providing education and awareness programs, and involving healthcare professionals in promoting digital health literacy.eninfo:eu-repo/semantics/openAccessTıbbi İnformatikTemel Sağlık HizmetleriArticle14496997410.5455/medscience.2025.06.1521369787