Nawaz, ZahidGurbuz, NevinZafar, Muhammad NaveedTahir, Muhammad NawazOzdemir, IsmailTrovitch, Ryan J.2024-08-042024-08-0420240022-28601872-8014https://doi.org/10.1016/j.molstruc.2024.139239https://hdl.handle.net/11616/102109A mild catalytic protocol for aldehyde, amine, and alkyne coupling (A3-coupling) allows for the selective synthesis of propargyl amines using 5,6-dimethylbenzimidazole-derived N-heterocyclic carbene (BNHC) silver(I) catalysts. A series of BNHC Ag(I) halide complexes were synthesized and their structures have been elucidated through the use of multinuclear NMR and FT-IR spectroscopy. Furthermore, the pseudo-linear geometry of two different compounds was substantiated by single-crystal X-ray diffraction. Silver-based A3-coupling was achieved for both acyclic and cyclic secondary amines using a diverse set of alkynes to afford propargyl amines with yields of up to 95 %. The present approach is environmentally benign and water is generated as the sole byproduct.eninfo:eu-repo/semantics/closedAccessN -Heterocyclic carbeneSilver complexesA3-couplingPropargyl amineArticle131810.1016/j.molstruc.2024.1392392-s2.0-85198026743Q2WOS:001269206000001N/A