Alnasser, SarahTouj, NedraAlomar, SulimanMansour, LamjedSauthier, MathieuGurbuz, NevinOzdemir, Ismail2024-08-042024-08-0420241751-82531751-7192https://doi.org/10.1080/17518253.2024.2370268https://hdl.handle.net/11616/102100In this work, we synthesized a series of six unsymmetrical benzimidazolium salts 2 and their pyridine-enhanced precatalyst preparation stabilization and initiation (PEPPSI)-themed palladium N-heterocyclic carbene complexes [PdCl2(NHC)(Py)]. All the products were isolated in satisfactory yields (75-85%). The synthesis of these novel palladium PEPPSI complexes involved in reacting NHC precursors with PdCl2 in pyridine at 60 degrees C in the presence of excess K2CO3. The structures of all compounds have been characterized by H-1 NMR, C-13 NMR, HRMS and IR spectroscopy, as well as elemental analysis techniques, which support the proposed structures. The catalytic activity of the six complexes was assessed in the Suzuki-Miyaura cross-coupling of phenylboronic acid and aryl halides. The reactions required only a low catalyst loading (0.1 mol%) and were carried out under mild aerobic conditions in a green, water-based solvent mixture.eninfo:eu-repo/semantics/closedAccessPalladium N-heterocyclic carben complexbenzimidazoleSuzuki-Miyaura cross couplingC-C bond formationwaterArticle17110.1080/17518253.2024.23702682-s2.0-85197716855Q1WOS:001263270600001N/A