Dolanbay, NihalOzkan, Meral2026-04-042026-04-0420250041-13451873-2623https://doi.org/10.1016/j.transproceed.2025.03.005https://hdl.handle.net/11616/109394Aim. Liver transplant patients experience several symptoms associated with immunosuppressive medications and have problems in medication adherence. This study aims to examine the effect of web-based education on symptoms and adherence to immunosuppressive medications in liver transplant patients. Materials and Methods. This is a randomized controlled trial study. The population of the study consisted of patients who had liver transplantation in a university hospital at least 2 months and at most 2 years before the interview (N = 116). The sample of the study consisted of a total of 90 liver transplant patients who were determined by a power analysis. The data were collected between January and July 2021 using a patient information form, the Modified Transplant Symptom Occurrence and Symptom Distress Scale-59 Items (MTSOSD-59), and the Immunosuppressive Medication Adherence Scale (IMAS). Results. Liver transplant patients in the experimental group were given a web-based education for 1 month. After the education, a significant decrease was observed in their symptom's occurrence and discomfort with symptoms scores and a significant increase in their immunosuppressive medication adherence scores, compared to that of those in the control group (P < .05). Conclusion. As a result, the web-based education reduced the symptoms and discomfort associated with immunosuppressive medications in liver transplant patients and increased their immunosuppressive medication adherence.eninfo:eu-repo/semantics/closedAccessNonadherenceArticle5758038094030090010.1016/j.transproceed.2025.03.0052-s2.0-105003759852Q3WOS:001501264500006Q40000-0002-7075-82500000-0003-3930-3490