Cetinkaya, BCetinkaya, EKucukbay, HDurmaz, R2024-08-042024-08-0419960004-4172https://hdl.handle.net/11616/93048Seventeen cyclic ureas containing imidazolidine and benzimidazoline nuclei were synthesised by the reaction of electron-rich olefins with appropriate group 16 elements (O, S, Se, Te). The compounds synthesised were identified by H-1, C-13-NMR, FT-IR and mass spectroscopic techniques and micro analysis. All compounds studied in this work were screened for their in vitro antimicrobial activity against standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC) 25922) and Pseudomonas aeruginosa (ATCC 27853). Eight of the compounds were found effective to inhibit the growth of Gram-positive bacteria (Enterococcus Faecalis and Staphylococcus aureus) at MIC values between 25-400 mu g/ml. None of the compounds exhibit antimicrobial activity against gram-negative bacteria (Escherichia coli; and Pseudmonas aeruginosa) at the concentrations studied (6.25-800 mu g/ml).eninfo:eu-repo/semantics/closedAccessantibioticsbenzimidazole derivativesimidazole derivativesurea derivatives, antimicrobial activity, cyclicArticle46121154115890067912-s2.0-0030479525N/AWOS:A1996WB49500011N/A