Akbulut, Sami2019-07-082019-07-082018Akbulut, S. (2018). Assessment of the relationship between clinical and histopathological features in cases of thyroidectomy. Cilt:89 Sayı:3, 199-205 ss.https://hdl.handle.net/11616/12382Aim: The aim of this study is to evaluate the relationship between clinical parameters and ultimate histopathologic features of patients underwent thyroid surgery. METHOD: Demographic and clinicopathologic parameters of patients who underwent thyroid surgery for benign or malignant disease in our clinic between June 2006 and March 2014 were retrospectively reviewed. Pearson's Chi-Square, Independent Sample T test, ROC Curve and Youden J Index were used to investigate whether there was any relationship between the clinical parameters and permanent histopathologic features of patients. RESULTS: A total of 3059 patients (Benign: 2727; Malign: 332) aged between 15 and 90 years were reviewed. The patients age was higher in malign group (mean +/- SD: 468 +/- 4.2) than benign group (mean +/- SD: 43.7 +/- 12.9 yr) and this difference was statistically significant (p <0.001). The nodule diameter (mean +/- SD: 30.8 +/- 13.5 mm) was greater in malign group than the benign group (mean +/- SD: 28.3 +/- 13.4 mm) and this difference was statistically significant (p = 0.002). The sensitivity and specificity rates of the most appropriate cut-off point (> 26 mm) for the nodule size were 60% and 49.05%, respectively. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of FNAB were calculated as 4.17 %, 100 %, 100 %, 89.96% and 90 %, respectively. CONCLUSION: This study showed that higher age and greater nodule diameter (> 26 mm) are associated with malignancyeninfo:eu-repo/semantics/restrictedAccessFıne-Needle-AspıratıonMultınodular GoıterNodule SızeCancerMalıgnancyRıskUltrasoundDıseaseThyroıdıtısPretordıcArticle893199205