Ozbey E.Asma D.2024-08-042024-08-0420191018-4619https://hdl.handle.net/11616/90900In last 30-35 years, it has been discovered that many organisms can live in environments consid-ered as extreme for mankind Since these microor-ganisms can live in the extreme environments, they are named as extiemophiles. One of the discovered microorganisms, Deinacaccus radiodurans, had drawn attention for its extraordinary capabilities and its potential of infinity. D. raJiodurans is re-sistant to genotoxic chemicals, oxidative damage, high-level ionization, ultraviolet radiation and de-hydratioa Because of these features one can name it polyextremophilic. In recent years, studies on bioremediation and related to heavy metal and detoxification of xenobiotics which cause serious environment problems, as well as genetic engineering have been intense. However, the reactive oxy-gen species, induced by UV and their effects, their cellular defense mechanisms against ROS and about antioxidative systems responsible for clean-ing of reactive oxygen species enough research has not been made.To this end: In Ecsherichia coli and radiation-resistant D. radiodurans bacteria were compared and tested effects on levels reduced glutathione (GSH) and antioxidant system of radiation. In both bacteria, enzyme activity and GSH levels has been determined after the different doses of ? radiation applications. In the end of our study, high activities in enzyme especially superoxide dismulase and catalase of D. radiodurans were observed depending on the different doses ? radiation applications. We were also observed that GSH quantity and other enzymes had a low activity in the cell. Moreover, it was determined that enzyme and GSH levels were decreased in E. coii depending on the radiation levels. © 2019 Parlar Scientific Publications. All rights reserved.eninfo:eu-repo/semantics/closedAccessCatalaseDeinococcus radioduransGlutathione redictaseGlutathione S-transferaseOxidative stressRadiationArticle288612561332-s2.0-85071666140N/A