Miman, OzlemOzcan, OzlemUnal, SueheylaAtambay, Metin2019-07-232019-07-232018Miman, O. Ozcan, O. Unal, S. Atambay, M. (2018). Toxoplasma gondii - obsessive -compulsive disorder relationship: is itdifferent in children?. Cilt:72. Sayı:7. 501-505 ss.https://hdl.handle.net/11616/12871Background and aim: Obsessive-compulsive disorder (OCD) is a common neuropsychiatric illness. Although the etiology of OCD is still unknown, recent investigations have associated development of OCD with infectious illness. Toxoplasma gondii (T. gondii) is a neurotropic protozoan parasite that causes infection of the central nervous system. In the last decade, a lot of researches have focused on the possible relationship between exposure to T. gondii and neuropsychiatric disorders such as schizophrenia. Therefore, in this study, it was aimed to investigate a possible association between Toxoplasma infection and OCD in children and adolescents.Methods: We selected 55 patients with OCD (aged between 7 and 16 years) and 59 healthy children and adolescents (aged between 7 and 16 years), and investigated the seropositivity rate for anti-Toxoplasma IgG antibodies by enzyme-linked immunosorbent assay.Results: The seropositivity rate for anti-T. gondii IgG antibodies among OCD patients (21.82%) was found to be higher than the rate in control group (15.25%). However, the difference between the OCD group and the control group was not statistically significant (p>.05).Conclusion: In contrast to studies in adult patients, the results of this study do not support the relationship between T. gondii and OCD children and adolescents.eninfo:eu-repo/semantics/openAccessInfectıonbehavıorschızophrenıaepıdemıologyadolescentsantıbodıesArticle72750150510.1080/08039488.2018.1514421