Carr B.I.2024-08-042024-08-04202297830308570289783030857011https://doi.org/10.1007/978-3-030-85702-8_26https://hdl.handle.net/11616/92143The idea that the mind responds to processes in the body and conversely, that the bodily functions can be influenced by the mind, is referred to as mind–body relationship. Recent studies in the diverse areas of metabolic, immune, endocrine, and gene expression effects from stress and depression have begun to permit a systems view of the effects of the emotions of cancer patients on specific cellular processes that could modulate cancer cell growth, positively or negatively. These concepts form a rational basis for considering the use of psychological therapy-cognitive, antidepressant, or relaxant not only for symptom management but possibly as part of total cancer patient management. We do not yet know that mind affects cancer biology and thus prognosis, but there are both clinical trials data and cancer patient biochemical data that point to that possibility. All patients live as part of a social and family context, with a two-way interaction between the perception of the mind of a body disease and the reaction of the mind to its significance, involving fear, hopefulness, spirituality, caring, and coping. These reactions are, in turn, capable of producing both destructive and helpful bodily effects. Many of these aspects of cancer patient and caregiver concerns and their management are addressed in this chapter. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.eninfo:eu-repo/semantics/closedAccessCancer survivorLynch syndromeReligious copingTranscutaneous electrical nerve stimulationVascular endothelial growth factorBook Chapter44746010.1007/978-3-030-85702-8_262-s2.0-85169350276N/A