Durmuş M.To?al T.Türköz A.Gedik E.Özturk E.Ersoy M.Ö.2024-08-042024-08-0420011016-5150https://hdl.handle.net/11616/90846This study was undertaken to evaluate the effects of lidocaine and alcalinized lidocaine filled endotracheal tube cuffs on extubation responses. Thirty five patients of Asa class I-II undergoing elective surgery were included. They were randomly assigned into three groups. After tracheal intubation, the endotracheal tube cuff was filled with one of the following solutions: serum physiologic (group A, n:12), 4 % lidocaine (group B, n:12) and 4 % lidocaine 4 ml + 8.4 % NaHCO3 1 mL (group C, n:11). Changes in heart rate, systolic, mean and diastolic arterial pressures were measured before and 1.3 and 5 min after tracheal extubation. Side effects such as coughing, sore throat, laryngospasm, bronchospasm, nausea and vomiting was evaluated after tracheal extubation and in recovery period. There was no statistically significant difference between three groups regarding to hemodynamic changes and adverse effects. We concluded that filling the endothraceal tube cuff with lidocaine or alcalinized lidocaine can not affect the heart rate and blood pressure increase which are seen after extubation and can not reduce the frequency of other side effects.trinfo:eu-repo/semantics/closedAccessDiffusionEndotracheal tube cuffExtubationLidocaineArticle2952062092-s2.0-0034944115N/A