Totan, YÇekiç, OBorazan, MUz, ESögüt, SAkyol, Ö2024-08-042024-08-0420010007-1161https://doi.org/10.1136/bjo.85.12.1426https://hdl.handle.net/11616/93348Aims-To evaluate alteration of plasma malondialdehyde (MDA) and nitric oxide (NO) levels in patients with exudative age related macular degeneration (ARMD). Methods-Plasma. nitrite plus nitrate concentrations as an index of plasma NO levels and plasma MDA level as a marker of lipid peroxidation were measured in patients with exudative ARMD and age and sex matched healthy subjects. Results-Significantly higher MDA and lower NO levels were detected in plasma of patients with ARMD compared with their controls (p=0.01, p=0.001, respectively). Conclusion-The results may support involvement of oxidative damage and vascular theory in the pathogenesis of ARMD as part of the ageing process.eninfo:eu-repo/semantics/openAccessOcular Blood-FlowRetinal Function RecoveryLipid-PeroxidationSynthase InhibitionAntioxidant EnzymesResistanceVitaminSerumArticle8512142614281173451310.1136/bjo.85.12.14262-s2.0-0035670811N/AWOS:000172605300010Q2