Kizilay, Fatma NurAydinbelge, MustafaDemirbuga, SezerKolcakoglu, KevserIldiz, NilayDayan, Serkan2026-04-042026-04-0420260109-56411879-0097https://doi.org/10.1016/j.dental.2025.11.008https://hdl.handle.net/11616/109658Objectives While compomers are widely used in pediatric dentistry, their antibacterial potential and fluoride release remain limited. This study aimed to evaluate the antibacterial and mechanical properties of compomers modified with different concentrations of calcium fructoborate-loaded mesoporous silica (CF@SBA-15) nanoparticles. Methods CF was synthesized via the Miljkovi & cacute; method and loaded into SBA-15. The resulting CF@SBA-15 nanomaterial was incorporated into a compomer at 0.5 % (Group 1) and 1.0 % (Group 2) by weight. Surface roughness, microhardness, and degree of conversion (DC) were evaluated. Characterization was performed using FT-IR, SEM-EDX, and TGA analyses. Boron release was quantified at 1, 24, 72, and 96 h using ICP-MS. Antibacterial activity against Streptococcus mutans and Lactobacillus casei was assessed by the direct contact test (DCT). Statistical significance was set at p < 0.05. Results Surface roughness and microhardness values increased significantly with higher CF@SBA-15 concentrations (p < 0.001), with Group 2 exhibiting the highest mean values. DC was significantly higher in both experimental groups than in the control (p = 0.009). Boron release demonstrated a progressive, concentration-dependent pattern, with Group 2 showing greater cumulative release (p = 0.009). Both nanoparticle-modified groups exhibited significantly stronger antibacterial effects compared with the control (p < 0.01). Conclusions Incorporating CF@SBA-15 nanoparticles into compomers enhanced antibacterial efficacy while preserving the essential physicochemical integrity of the material.eninfo:eu-repo/semantics/closedAccessAntibacterial propertyCalcium fructoborateCompomerSBA-15Secondary cariesArticle4234514594124158810.1016/j.dental.2025.11.0082-s2.0-105021947959Q1WOS:001685632000001Q10000-0003-2596-8678