Bilgiç, YılmazHarputluoğlu, MuratKutlu, ODemirel, UlviGül, MehmetOtlu, BarışTemel, İsmailGürsoy, S.Dertli, RamazanSelçuk, Engin BurakYılmaz, İsmetKilis, Tuba2017-07-102017-07-102015Bilgiç, Y. Harputluoğlu, M. Kutlu, O. Demirel, U. Gül, M. Otlu, B. Temel, İ. Gürsoy, S. Dertli, R. Selçuk, E. B. Yılmaz, İ. Kilis, T. (2015). Effects of Lycium barbarum on bacterial translocation in thioacetamide induced liver injury in rats. European Journal of Inflammation, 13(3), 154–163.1721-727Xhttp://eji.sagepub.com/lookup/doi/10.1177/1721727X15618413https://hdl.handle.net/11616/7358Background and study aim: The aim of the present study was to investigate the effects of Lycium barbarum (LB) on bacterial translocation (BT) frequency in thioacetamide (TAA)-induced liver injury in rats. Materials and methods: Group 1 was the control. In group 2 (TAA), rats received TAA daily for 3 days. In group 3 (TAA+LB), Lycium barbarum was administered orally 25 mg/kg for 21 days prior to the first TAA injection. In group 4 (LB), rats received only Lycium barbarum. Results: In our study, Lycium barbarum treatment did not attenuate liver damage. Lycium barbarum treatment decreased ileal E. coli counts and intestinal damage but it did not alter BT frequency. Conclusions: In conclusion, the effects of Lycium barbarum on BT may be related to ongoing severe liver damage in this model.eninfo:eu-repo/semantics/openAccessBacterial translocationLiver injuryLycium barbarumThioacetamideArticle13315416310.1177/1721727X15618413