Incidental gallbladder carcinoma during or after cholecystectomy

Abstract

Abstract:Aim: We aimed to present the patients who were diagnosed with benign gallbladder diseases preoperatively and performed laparoscopic or open cholecystectomy however detected gallbladder cancer during or after cholecystectomy. Material and Methods: We performed 1074 cholecystectomies for benign pathologies between January 2012 and December 2017. Incidentally diagnosed gallbladder cancers were retrospectively analyzed in term of demographic features, clinical presentations, pathological stages, treatment methods and outcomes. Results: Among the 1074 patients participating in this study, 727 (67.6%) were females and 347 (32.4%) were males with a median age 54.6 years (range: 18-92 years). Nine hundred and thirty-four (87%) of these 1074 patients were diagnosed with chronic cholecystitis and in 140 (13%) patients acute cholecystitis was detected. In 11 (8 females, median age: 67.4) patients, gallbladder cancer (four pT2, five pT3 and two pT4) was detected during or after cholecystectomy. Four (36.4%) patients diagnosed with acute cholecystitis and one (9%) with gallbladder perforation. Patients with acute cholecystitis symptoms (0.6% vs. 3.6%, p: 0.001) and aged (80 ≤) patients (0.7% vs 5.3%, p< 0.001) had a higher risk for incidental gallbladder carsinoma following cholecystectomy. Conclusion: Suspicion of gallbladder cancer especially in elderly patients and patients with acute cholecystitis symptoms had more risk for incidental gallbladder cancers at cholecystectomy.