Özet:
Aim: The use of intravenous sedation and analgesia during interventional radiological procedures is increasing. Sedation and
analgesia should minimize patients’ negative psychological reactions caused by fears and anxiety. Also they should relieve pain and
provide patients a safe and comfortable environment.
The aim of this study was to compare the efficacy and safety of two drugs and methods used for moderate sedation during
radiological procedures.
Material and Methods: Sixty patients, with American Society of Anesthesiologists scores (ASA) I-II-III, undergoing interventional
radiology procedures were included in this study. The patients were administered remifentanil bolus (0.2 µg.kg-1) followed by
remifentanil infusion (0.05 µg.kg-1.min-1) in Group R, 2.5mL loading dose (25 mg propofol–25 µg remifentanil) and a 1mL bolus
dose (10 mg propofol–10 µg remifentanil) via patient-controlled analgesia/sedation (PCAS) device in Group PR. All the patients’
sedation levels were assessed with the Ramsey Sedation Scale (RSS), pain levels were assessed with Visual Analog Scale (VAS).
Their recoveries were assessed with the modified Aldrete score (MAS) at 5 min intervals.
Results: Although a significant difference was noted between the groups for RSS values at 5, 10, 20, 25, and 30th minutes during the
procedure (P<0.05), there was no significant difference in VAS, anxiety levels and MAS (P > 0.05).
Conclusion: Both propofol–remifentanil PCAS and remifentanil infusion provide sufficient moderate sedation.
