Abstract:
Aim: The relationship between inflammation and the development of atrial fibrillation and the relationship between platelet to
lymphocyte ratio and mean platelet volume in relation to inflammation were investigated in patients with atrial fibrillation after
isolated coronary artery bypass graft operation.
Material And Methods: Clinical and laboratory data of 132 patients, who did not have preoperative atrial fibrillation and underwent
isolated coronary artery bypass graft operation using cardiopulmonary pump, were analyzed retrospectively. Patients were divided
into two groups as patients with developed atrial fibrillation and those without atrial fibrillation. Concomitant diseases, preoperative
drug use, echocardiographic and angiographic findings, preoperative, intraoperative and postoperative laboratory parameters were
obtained from medical records and compared statistically.
Results: Of the 132 patients, 68 with atrial fibrillation (mean age: 68.3+/-10.7 years, 50 males and 18 females) and 64 patients
without atrial fibrillation (mean age: 64.5+/-9.8 years, 55 males and 9 females) were identified, and difference in the mean age
was statistically significant (p=0.016). Postoperative platelet to lymphocyte ratio and mean platelet volume values (280.3+/-112.3;
9.9+/-1.7) were also significantly higher in those with atrial fibrillation group than preoperative values (129.2+/-49.3; 9.6+/-1.6,
p<0.0001, p<0.0009).
Conclusıon: According to our study higher values of postoperative platelet to lymphocyte ratio and mean platelet volume are
correlated with development of atrial fibrillation after coronary artery bypass graft operation
