Predictive value of platelet to lymphocyte ratio and mean platelet volume in atrial fibrillation after isolated coronary artery bypass graft operation

Abstract

Aim: The relationship between inflammation and the development of atrial fibrillation and the relationship between platelet to lymphocyte ratio and mean platelet volume in relation to inflammation were investigated in patients with atrial fibrillation after isolated coronary artery bypass graft operation. Material And Methods: Clinical and laboratory data of 132 patients, who did not have preoperative atrial fibrillation and underwent isolated coronary artery bypass graft operation using cardiopulmonary pump, were analyzed retrospectively. Patients were divided into two groups as patients with developed atrial fibrillation and those without atrial fibrillation. Concomitant diseases, preoperative drug use, echocardiographic and angiographic findings, preoperative, intraoperative and postoperative laboratory parameters were obtained from medical records and compared statistically. Results: Of the 132 patients, 68 with atrial fibrillation (mean age: 68.3+/-10.7 years, 50 males and 18 females) and 64 patients without atrial fibrillation (mean age: 64.5+/-9.8 years, 55 males and 9 females) were identified, and difference in the mean age was statistically significant (p=0.016). Postoperative platelet to lymphocyte ratio and mean platelet volume values (280.3+/-112.3; 9.9+/-1.7) were also significantly higher in those with atrial fibrillation group than preoperative values (129.2+/-49.3; 9.6+/-1.6, p<0.0001, p<0.0009). Conclusıon: According to our study higher values of postoperative platelet to lymphocyte ratio and mean platelet volume are correlated with development of atrial fibrillation after coronary artery bypass graft operation