Özet:
Dexmedetomidine is a preferred anesthetic agent
in otological surgery because it provides controlled hypotension
and good surgical field visibility. The aim of this study was to
evaluate the influence of this novel agent on middle ear pressure.
STUDY DESIGN AND SETTING: This prospective clinical
trial was performed in 60 patients who were scheduled for elective
surgery. They received dexmedetomidine or saline infusion for 20
minutes before induction of anesthesia. Tympanometric measurements
were recorded for both ears at preoperative, intraoperative,
and postoperative states.
RESULTS: Mean difference of tympanometric peak pressure
from baseline was statistically significant between dexmedetomidine
and control group at the 30th minute of operation (24.8 daPa,
P 0.003 for right ear; 20.5 daPa, P 0.02 for left ear) and at the
end of the operation (25.8 daPa, P 0.01 for right ear; 28.1 daPa,
P 0.004 for left ear).
CONCLUSIONS: Dexmedetomidine anesthesia raises the tympanometric
parameters, but they never exceed the limits of normal.
© 2007 American Academy of Otolaryngology–Head and Neck
Surgery Foundation. All rights reserved.
