Abstract:
We investigated the presence of Helicobacter
pylori in laryngeal cancer specimens to reveal whether
or not this is a risk factor in the development of squamous
cell carcinoma of the larynx. Methods: Sixty-nine
total laryngectomy specimens with the pathologic diagnosis
of squamous cell carcinoma and 30 laryngeal tissue
samples that had been taken for the investigation of
nonneoplastic (polyp, nodule) diseases were studied.
Specimens of both tumor and control groups were
stained with hematoxylin-eosin and modifi ed Giemsa
stains, and then they were examined under a light microscope.
Results: In both groups, H. pylori could not be
found in any of the cases. Conclusion: The histologic examination
of our series did not reveal any clue related to
the possible etiologic association between H. pylori and
squamous cell carcinoma of the larynx.