Abstract:
Gilbert’s syndrome (GS) is a common cause of inherited benign unconjugated hyperbilirubinemia
that occurs in the absence of overt hemolysis, other liver function test
abnormalities, and structural liver disease. GS may not affect a patient’s selection for
living-donor liver transplantation (LDLT). Between February 2005 and April 2011, 446
LDLT procedures were performed at our institution. Two of the 446 living liver donors
were diagnosed with GS. Both donors underwent extended right hepatectomies, and
donors and recipients experienced no problem in the postoperative period. Their serum
bilirubin levels returned to the normal range within 1–2 weeks postoperatively. In our
opinion, extended right hepatectomy can be performed safely in living liver donors with GS
if appropriate conditions are met and remnant volume is 30%. Livers with GS can be
used successfully as grafts in LDLT recipients.
