Abstract:
The transplantation of organs from donors who have
undergone shunt surgery or craniotomy for a malignant
central nervous system (CNS) tumor is controversial.
We report a case of Kaposi’s sarcoma (KS) developing
as a result of immunosuppression in the recipient of a
liver transplant from a donor who underwent craniotomy
and ventriculoperitoneal shunt surgery for primary
CNS lymphoma. Polymerase chain reaction assay did
not isolate human herpes virus-8 in the Kaposi lesions.
To our knowledge, this is the only case ever reported of
KS developing after liver transplantation from a donor
with lymphoma. Thus, with appropriate screening to
exclude possible dissemination, patients with a history
of high-grade primary CNS lymphoma treated by ventriculoperitoneal
shunt and craniotomy may be accepted
as donors.
