Abstract:
Primary intestinal lymphoma with spontaneous
perforation and after systemic chemotherapy is rare. The
present study summarizes retrospectively the outcome of
eight free intestinal perforated patients diagnosed with intestinal
non-Hodgkin’s lymphoma. Two patients had a history
of systemic chemotherapy before perforation. The most
common symptoms of the patients were abdominal pain,
nausea, vomiting, weight loss, and fever. Sites of perforation
were ileum in four, jejunum in two, cecum in one, and
sigmoid colon in one patient. Synchronous lymphoma was
present in three patients. The perforation was closed by primary
closure in three patients. Resection/anastomosis was
performed in four patients and sigmoid colostomy was performed
in one patient. Three patients were lost due to leakage
or septicemia. Intestinal lymphoma might be kept in mind
as a cause in free intestinal perforations. Because of the high
mortality rate early diagnosis and treatment are important to
improve the prognosis of bowel perforation in patients with
non-Hodgkin’s lymphoma.
