Abstract:
Background: Oral allergy syndrome (OAS) is a unique allergic reaction to food, which is caused by cross-reactivity
between proteins in fresh fruits or vegetables and pollens. Predisposing factors for OAS are not well known in
patients with seasonal allergic rhinitis.
Objective: Identify the probable risk factors for OAS in patients with seasonal allergic rhinitis.
Study Design: One hundred and eleven consecutive patients with seasonal allergic rhinitis were included. Patients
were evaluated in terms of symptom scores and skin prick test positivity scores. Prick-by-prick tests with the fresh
fruit or vegetable were carried out in patients who describe oral allergy syndrome. Patients with OAS and without
OAS were compared statistically.
Results: OAS was more frequent in females than males (p=0.01). Odds ratio for gender (male/female) was 3.80
(95% confidence interval: 1.28-11.32). Within nasal symptoms, only nasal itching was related with OAS (P<0.05).
The logistic regression analysis revealed a significant association between the prevalence of the OAS and age,
asthma, TSS and TSTP (p<0.05).
Conclusion: Not all patients with seasonal allergic rhinitis develop OAS. It is likely that, patients with OAS have
some additional risk factors other than atopy.
