Coexistence of hashimoto's thyroiditis with papillary thyroid carcinoma: a single center experience

Abstract

Abstract Aim: A positive correlation between Hashimoto's thyroiditis (HT) and papillary thyroid cancer (PTC) is determinated in studies based on histopathological examination of the thyroidectomy materials, but this correlation is not determinated in studies based on Fine Niddle Aspiration Biopsy (FNAB). In this study, the histopathologic results of bilateral total thyroidectomy (TT) specimens were studied for outcomes of PTC association with HT and its relationship with clinical and pathological prognostic factors. Material and Methods: Demographic data, thyroidectomy indications and pathology results of 568 patients with performed TT between April 2009 March 2016 were collected. PTC identified patients, were evaluated in terms of HT association. In these patients, the prognostic factors were evaluated according to coexistence of HT. Results: The average age of the patients was 48.9 years and M / F ratio was 1: 3.5. HT was detected in 36 patients and PTCin 121 patients by histopathological examinations. PTC incidence in HT group was higher than non-HT group. (p = 0.025). HT incidence in PTC group was higher than non-PTC group (p = 0.025).When compared in terms of demographic and prognostic data of PTC patiens,no statistically significant difference was detected between PTC with and without HT groups. Conclusion: PTC detection rate in patients with HT, who has indication for thyroidectomy is higher than non-HT patients. HT patients (especially female sex), should be followed closely, in terms of the development of malignant nodules. Keywords: Hashimoto's Thyroiditis; Papillary Thyroid Cancer; Thyroidectomy.