dc.contributor.author |
Kılıç, Süleyman |
|
dc.contributor.author |
Karadag, N. |
|
dc.contributor.author |
Ergin, H. |
|
dc.contributor.author |
Altunoluk, B. |
|
dc.date.accessioned |
2020-07-16T11:40:58Z |
|
dc.date.available |
2020-07-16T11:40:58Z |
|
dc.date.issued |
2014 |
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dc.identifier.citation |
Kilic, S., Karadag, N., Ergin, H., Altunoluk, B. Effects of goserelin treatment on microvessel density and blood loss associated with transurethral resection of the prostat. (2014). Journal of Clinical and Analytical Medicine. |
tr_TR |
dc.identifier.issn |
13090720 |
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dc.identifier.other |
DOI: 10.4328/JCAM.1294 |
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dc.identifier.uri |
http://abakus.inonu.edu.tr/xmlui/handle/123456789/17017 |
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dc.description |
Journal of Clinical and Analytical Medicine
Volume 5, Issue 3, May 2014, Pages 229-233 |
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dc.description.abstract |
Aim: To determine the effects of one dose goserelin before transurethral resection of the prostate (TUR-P) on blood loss and microvessel density (MVD) of prostatic suburethral tissues in the patients with benign prostatic hyperplasia (BPH). Material and Method: The patients who planned to have a TUR-P were randomly divided into two groups. Group-1 consisted of 18 patients who were pretreated with 3,6 mgr subcutaneous injection of goserelin acetate one month before the operation. Group-2 was constructed from 21 patients without goserelin acetate pretreatment. The amount of intraoperative haemorrhage was calculated. Total blood loss, total blood loss/duration of surgery and total blood loss/gram of resected tissue were calculated for each patient. Sections from the prostatic suburethral tissues were examined for microvessel density. Results: Quantitative decreases in Hb were greater in group 1 than in group 2, and mean Hb level was statistically significantly lower in group 1 than in group 2 at the control just after the operation (p=0.028). Although all the differences were statistically insignificant, Hb concentration in irrigation fluid and total blood loss during surgery were higher in the group 1 than in the group 2, contrarily, blood loss by duration of TURP and blood loss by weight of resected prostate tissue were less in the group 1 than in the group 2. The MVD was significantly lower in group 2 than in the group 1. Discussion: Single dose goserelin treatment given for one month is not effective in reducing blood loss during TURP and has not suppressive effects on MVD in prostatic tissues. |
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dc.language.iso |
en |
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dc.publisher |
Journal of Clinical and Analytical Medicine |
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dc.subject |
Benign prostatic hyperplasia |
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dc.subject |
Blood loss |
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dc.subject |
Microvessel density |
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dc.subject |
Transurethral resection of prostate |
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dc.title |
Effects of goserelin treatment on microvessel density and blood loss associated with transurethral resection of the prostat |
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dc.title.alternative |
Goserelin tedavisinin prostati{dotless}n transüretral rezeksiyonu ile i̇lişkili kan kaybi{dotless} ve mikrovasküler dansite üzerindeki etkisi |
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dc.type |
Article |
tr_TR |