Nitrik oksit (NO) makrofajların sitotoksik etkisinin ortaya çıkmasında rol almaktadır. NO’in yapımını nitrik oksit sentaz (NOS) enzimi katalize etmektedir. Sitozolde bulunan bu enzimin, enzimi kodlayan genler, hücre veya ...

Selenoprotein R (SelR) is a mammalian selenocysteine-containing protein with no known function. Here we report that cysteine homologs of SelR are present in all organisms except certain parasites and hyperthermophiles, ...

The aim of this study was to investigate in rats whether preoperative orogastric administration of low doses of cholera toxin would influence the mechanical strength of experimental colonic anastomosis on the basis of ...

Lipopolisakkaridin (LPS veya endotoksin) toksik etkilerinden lipid A kısmı sorumludur. Lipid A’nın yapısal analogları ve öncül moleküllerinin tanımlanmasından sonra bunların LPS’nin biyolojik etkilerine karflı ...

Nitric oxide (NO) is an important mediator involved in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS). We examined the effect of glatiramer acetate (GA), an agent with ...

Pancreatic cancer is characterized initially by non-specific abdominal symptoms followed by rapid tumor progression. Although chronic pancreatitis is a benign disorder, it can be one of the causative factors of pancreatic ...

Influenza A virus infection is a major source of morbidity and mortality worldwide. Current means of control for influenza are based on prophylaxis by vaccines and on treatment by the available specific influenza neuraminidase ...

Inflammatory bowel diseases are characterized by detrimental immune reactivity in the gut and imbalance between proinflammatory and antiinflammatory reactivity. In an attempt to downregulate inflammatory bowel disease, we ...