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    Anomalous origin of the left coronary artery from the right coronary sinus
    (Annals of Thoracic and Cardiovascular Surgery, 2012) Çolak, Mehmet Cengiz; Erdil, Nevzat; Dişli, Olcay Murat; Kahraman, Ercan; Battaloğlu, Bektaş
    Anomalous origin of the left coronary artery (LCA) from the right coronary artery sinus is a rare congenital coronary anomaly. We report a case of a 48-year-old symptomatic man who was admitted to our clinic with a history of hypertension, type 2 diabetes mellitus, myocardial infarction and hypercholesterolemia. Coronary angiography was performed revealing anomalous left coronary artery from the right coronary artery sinus. In addition, stenosis of RCA and well developed stenotic diagonal artery were detected with coronary angiography. We performed coronary by-pass with left internal mammarian artery to diagonal artery and vena saphena to right coronary artery (RCA). Both coronary angiography and intraoperative view should be evaluated well in patients with anomalous of the coronary artery
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    The arteriovenous fistulas for hemodialysis complications in short and long term in department of cardiovascular surgery clinic turgut ozal medical center
    (Journal of Turgut Ozal Medical Center, 2011) Çolak, Mehmet Cengiz; Dişli, Olcay Murat; Erdil, Nevzat; Cihan, H. Berat; Battaloğlu, Bektaş
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    Ateroskleroz un tahmini için bir yapay sinir ağı
    (Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2005) Çolak, Cemil; Çolak, Mehmet Cengiz; Atıcı, Mehmet Ali
    Amaç: Bu çalışmada, ateroskleroz’un tahmin edilebilmesi için bir yapay sinir ağı oluşturulması amaçlanmıştır. Gereç ve Yöntem: Haziran 2003 ile Kasım 2003 tarihleri arasında, kesikli ve sürekli değişkenlerden oluşan yirmi adet klinik parametre, radial arterde ateroskleroz saptanan on hasta ile radial arterde ateroskleroz saptanmayan on beş hastadan elde edilmiştir. Yapay sinir ağları, ateroskleroz verilerine uygulanmıştır. Bulgular: Geliştirilen yapay sinir ağının toplam ayrımsama oranı, eğitim ve test verisinde sırasıyla % 86.6 ve % 80 olarak bulunmuştur. Sonuç: Yapay sinir ağlarının ateroskleroz’un tahmin edilmesinde oldukça yararlı olacağı sonucuna varılabilir. Ancak örnek sayısının az olması göz önünde bulundurulduğunda, daha güvenilir sonuçlar elde edebilmek için örnek sayısının artırılması önerilebilir. Anahtar sözcükler: Ateroskleroz, Klinik parametreler, Yapay sinir ağları Aim: An artificial neural network was aimed to develop for the prediction of atherosclerosis. Material and Method: Between June 2003 and November 2003, twenty clinical parameters containing continuous and discrete variables were obtained ten patients for whom atherrosclerosis was determined in radial artery and fifteen patients for whom atherrosclerosis does not exist. Artificial neural network was applied to atherosclerosis data. Results: Accuracy values of artificial neural network on training and testing data were 86.6% and 80% respectively. Conclusion: The developed artificial neural network may be very useful for the prediction of atherosclerosis. However, in view of small sample size, it may be proposed to increase the sample size to obtain more reliable results. Key words: Artificial neural network, Atherosclerosis, Clinical parameters
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    Aterosklerozun tahmini için bir yapay sinir ağı
    (Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2005) Çolak, Cemil; Çolak, Mehmet Cengiz; Atıcı, M.Ali
    Amaç: Bu çalışmada, ateroskleroz’un tahmin edilebilmesi için bir yapay sinir ağı oluşturulması amaçlanmıştır. Gereç ve Yöntem: Haziran 2003 ile Kasım 2003 tarihleri arasında, kesikli ve sürekli değişkenlerden oluşan yirmi adet klinik parametre, radial arterde ateroskleroz saptanan on hasta ile radial arterde ateroskleroz saptanmayan on beş hastadan elde edilmiştir. Yapay sinir ağları, ateroskleroz verilerine uygulanmıştır. Bulgular: Geliştirilen yapay sinir ağının toplam ayrımsama oranı, eğitim ve test verisinde sırasıyla % 86.6 ve % 80 olarak bulunmuştur. Sonuç: Yapay sinir ağlarının ateroskleroz’un tahmin edilmesinde oldukça yararlı olacağı sonucuna varılabilir. Ancak örnek sayısının az olması göz önünde bulundurulduğunda, daha güvenilir sonuçlar elde edebilmek için örnek sayısının artırılması önerilebilir. Anahtar sözcükler: Ateroskleroz, Klinik parametreler, Yapay sinir ağları Aim: An artificial neural network was aimed to develop for the prediction of atherosclerosis. Material and Method: Between June 2003 and November 2003, twenty clinical parameters containing continuous and discrete variables were obtained ten patients for whom atherrosclerosis was determined in radial artery and fifteen patients for whom atherrosclerosis does not exist. Artificial neural network was applied to atherosclerosis data. Results: Accuracy values of artificial neural network on training and testing data were 86.6% and 80% respectively. Conclusion: The developed artificial neural network may be very useful for the prediction of atherosclerosis. However, in view of small sample size, it may be proposed to increase the sample size to obtain more reliable results.
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    A comparison of different treatment managements in patients with acute deep vein thrombosis by the effects on enhancing venous outflow in the lower limb
    (Medical Science and Technology, 2009) Rahman, Ali; Çolak, Mehmet Cengiz; Üstünel, Latif; Koç, Mustafa; Kocakoc, Ercan; Çolak, Cemil
    Background: This study aimed at evaluating the benefits of the traditional management of acute deep vein thrombosis (DVT), subcutaneous (sc) administration of low-molecular-weight heparin (LMWH) one dose a day and bed rest, and LMWH with compression stocking and early ambulation compared with LMWH with pneumatic compression (PC) in patients with DVT. Material and Method: Forty-eight consecutive patients with DVT were separated evenly into four groups. Group A received intravenous unfractionated heparin, group B received sc injection of enoxaparin sodium and bed rest, group C received sc injection of enoxaparin sodium and thigh-length compression stockings, and group D received sc injection of enoxaparin sodium and PC for periods of up to 7 days. Results: Comparing days 0 and 7, significant differences were determined in each group regarding differences in circumference of the two legs at the thigh and calf levels and the visual analogue scale (VAS) of pain, and in groups B, C, and D regarding the Lowenberg test for diseased and healthy legs (p<0.001). Between days 0 and 7, significant differences were found in the superficial femoral artery, superficial femoral vein, femoral vein, and the popliteal vein within groups A and D (p<0.05). Conclusions: Traditional management, sc administration of low-molecular-weight heparin, and pneumatic compression of patients with DVT led to a faster reduction of leg swelling and pain and to increased volume flow through the deep veins of the legs.
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    A comparison of different treatment managements in patients with acute deep vein thrombosis by the effects on enhancing venous outflow in the lower limb
    (Medical Science and Technology, 2009) Rahman, Ali; Çolak, Mehmet Cengiz; Üstünel, Latif; Koç, Mustafa; Kocakoç, Ercan; Çolak, Cemil
    Background: This study aimed at evaluating the benefits of the traditional management of acute deep vein thrombosis (DVT), subcutaneous (sc) administration of low-molecular-weight heparin (LMWH) one dose a day and bed rest, and LMWH with compression stocking and early ambulation compared with LMWH with pneumatic compression (PC) in patients with DVT. Material and Method: Forty-eight consecutive patients with DVT were separated evenly into four groups. Group A received intravenous unfractionated heparin, group B received sc injection of enoxaparin sodium and bed rest, group C received sc injection of enoxaparin sodium and thigh-length compression stockings, and group D received sc injection of enoxaparin sodium and PC for periods of up to 7 days. Results: Comparing days 0 and 7, significant differences were determined in each group regarding differences in circumference of the two legs at the thigh and calf levels and the visual analogue scale (VAS) of pain, and in groups B, C, and D regarding the Lowenberg test for diseased and healthy legs (p<0.001). Between days 0 and 7, significant differences were found in the superficial femoral artery, superficial femoral vein, femoral vein, and the popliteal vein within groups A and D (p<0.05). Conclusions: Traditional management, sc administration of low-molecular-weight heparin, and pneumatic compression of patients with DVT led to a faster reduction of leg swelling and pain and to increased volume flow through the deep veins of the legs.
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    The comparison of logistic regression model selection methods for theprediction of coronary artery disease
    (Anadolu Kardıyolojı Dergısı-The Anatolıan Journal Of Cardıology, 207) Çolak, Cemil; Çolak, Mehmet Cengiz; Orman, Mehmet N.
    Amaç: Bu çal›flma, koroner arter hastal›¤›n›n (KAH) tahmini için lojistik regresyon modeli seçim yöntemlerinin karfl›laflt›r›lmas› amac›yla yap›lm›flt›r. Yöntemler: Koroner arter hastal›¤› verileri, 2001 y›l›nda ‹nönü Üniversitesi T›p Fakültesi Kardiyoloji bölümüne müracaat eden ard›fl›k 237 bireyden elde edilmifltir. Lojistik regresyon modeli seçim yöntemleri, kesikli ve sürekli ba¤›ms›z de¤iflkenlerden oluflan KAH verilerine uygulanm›flt›r. Modellerin uyum iyili¤i testi Hosmer-Lemeshow istatisti¤i ile yap›lm›flt›r. Tahminlenen modellerin karfl›laflt›r›lmas›nda olabilirlik oran istatisti¤i kullan›lm›flt›r. Bulgular: Her bir model seçim yöntemine ait duyarl›l›k, seçicilik ve do¤ruluk oranlar› % 91.9’dan daha yüksek bulunmufltur. Modellerin KAH verilerini baflar›l› bir flekilde aç›klad›¤› Hosmer-Lemeshow uyum iyili¤i testi sonuçlar› ile do¤rulanm›flt›r. Koroner arter hastal›¤› ile iliflkili etkenler belirlenip, sonuçlar yorumlanm›flt›r. Sonuç: Lojistik regresyon modeli seçim yöntemleri KAH’›n tahmin edilmesinde oldukça baflar›l› sonuçlar vermifltir. Olabilirlik oran istatisti¤i sonuçlar›na göre KAH’›n tahmini için ad›msal yöntemlerin Enter yönteminden daha iyi oldu¤u saptanm›flt›r. Yafl, diyabetes mellitus, hipertansiyon, aile öyküsü, sigara kullan›m›, düflük dansiteli lipoprotein, trigliserid, stres ve obezite de¤iflkenleri KAH’› tahmin etmede kullan›labilir. (Anadolu Kardiyol Derg 2007; 7: 6-11) Anahtar kelimeler: Lojistik regresyon modeli seçim yöntemleri , koroner arter hastal›¤›, olabilirlik oran istatisti¤i
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    The comparison of logistic regression model selection methods for theprediction of coronary artery disease
    (Anadolu Kardiyoloji Dergisi- The Anatolian Journal of Cardiology, 2007) Çolak, Cemil; Çolak, Mehmet Cengiz; Orman, Mehmet N.
    Amaç: Bu çalışma, koroner arter hastalığının (KAH) tahmini için lojistik regresyon modeli seçim yöntemlerinin karşılaştırılması amacıyla yapılmıştır. Yöntemler: Koroner arter hastalığı verileri, 2001 yılında ‹nönü Üniversitesi Tıp Fakültesi Kardiyoloji bölümüne müracaat eden ardışık 237 bireyden elde edilmiştir. Lojistik regresyon modeli seçim yöntemleri, kesikli ve sürekli bağımsız değişkenlerden oluşan KAH verilerine uygulanmıştır. Modellerin uyum iyiliği testi Hosmer-Lemeshow istatistiği ile yapılmıştır. Tahminlenen modellerin karşılaştırılmasında olabilirlik oran istatistiği kullanılmıştır. Bulgular: Her bir model seçim yöntemine ait duyarlılık, seçicilik ve doğruluk oranları % 91.9’dan daha yüksek bulunmuştur. Modellerin KAH verilerini başarılı bir şekilde açıkladığı Hosmer-Lemeshow uyum iyiliği testi sonuçları ile doğrulanmıştır. Koroner arter hastalığı ile ilişkili etkenler belirlenip, sonuçlar yorumlanmıştır. Sonuç: Lojistik regresyon modeli seçim yöntemleri KAH’ın tahmin edilmesinde oldukça başarılı sonuçlar vermiştir. Olabilirlik oran istatistiği sonuçlarına göre KAH’ın tahmini için adımsal yöntemlerin Enter yönteminden daha iyi olduğu saptanmıştır. Yaş, diyabetes mellitus, hipertansiyon, aile öyküsü, sigara kullanımı, düşük dansiteli lipoprotein, trigliserid, stres ve obezite değişkenleri KAH’ı tahmin etmede kullanılabilir.
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    Coronary bypass surgery in patients with pulmonary hypertension assessment of early and long term results
    (Ann Thorac Cardiovasc Surgery, 2015) Akça, Barış; Erdil, Nevzat; Dişli, Olcay Murat; Dönmez, Köksal; Erdil, Feray; Çolak, Mehmet Cengiz; Battaloğlu, Bektaş
    Purpose: We aimed to evaluate the effects of preoperative pulmonary hypertension (PH) on early and long term results in patients undergoing coronary bypass surgery and the effects of coronary bypass surgery on PH. Methods: Among 2325 patients who underwent elective isolated coronary artery bypass surgery between March 2003 and March 2012, 287 patients with high preoperative pulmonary arterial pressure (PAP) ≥30 mmHg were examined. Patients’ data were obtained by retrospective examination of our clinic’s database. 69 patients who had complete parameters included in the study. Results: There was no increase in the New York Heart Association (NYHA) functional classification 84% of cases. Preoperative and postoperative values of the mean ejection fraction and mean PAP of patients was respectively 45.28 ± 9.67 (25–65), 46.03 ±12.4 (20–65) (p = 0.447), 36.67 ± 6.81 (30–60) mmHg, 37.81 ± 10.07 (20–70) mmHg (p = 0.378). The late mortality of cases was 5.79%. In our study, during 33.9 ± 17 (9–100) months follow up period, life expectancy was calculated as 94.7 months. Conclusion: Preoperative evaluation of these patients for appropriate medical treatment at peroperative and postoperative period, coronary bypass can be performed with low morbidity and mortality rates. In the late period after surgical revascularization PH showed no significant change and had no adverse effect on quality of life.
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    Derin ven trombozu sonrası asemptomatik pulmoner emboli tanısında ventilasyon/ perfüzyon sintigrafisi ve multidedektör bilgisayarlı tomografinin karşılaştırılması
    (2014) Yücedağ, Eflatun; Uysal, Ayhan; Burma, Oktay; Özgüler, İbrahim Murat; Çolak, Mehmet Cengiz; Ansal Balcı, Tansel
    Öz: Amaç: Pulmoner tromboemboli (PTE) sistemik venöz sistemde oluşan pıhtıların pulmoner vasküler yatağa göçü ile ortaya çıkan klinik tabloya verilen isimdir. Akut derin ven trombozu (DVT) sonrası ortalama %40-60 oranında asemptomatik PTE görülmekte ve bu durum sessiz klinik seyir nedeniyle fark edilmemektedir. Bu çalışmamızda akut alt ekstremite DVTsine bağlı gelişen asemptomatik PTE tanısında hala günümüzde önemli bir yer tutan ventilasyon-perfüzyon (V/P) sintigrafisi ile son yıllarda kullanılmaya başlanan multi-detektor bilgisayarlı tomografinin (MDBT) sensitivite ve spesifitesini karşılaştırmayı amaçladık. Yöntemler: Çalışma alt ekstremite akut DVT nedeniyle kliniğimize yatırılarak tedavisi planlanan 25 hastada ger- çekleştirildi. Gebeler, nüks DVT vakaları, müracaat esnasında semptomatik PTE tablosu olanlar, vena kavaya uzanım gösteren trombüsü olanlar, önceden geçirilmiş PTE öyküsü olanlar çalışmaya dahil edilmedi. Hastalarda DVT tanısı renkli doppler USG ile konulup, D-dimer testiyle teyit edildi. Hastalara yatışının 1.ve 8. günlerinde V/P sintigrafisi ve MDBT yapılarak asemptomatik PTE varlığı araştırıldı. Bulgular: Pulmoner tromboemboli açısından asemptomatik olan 25 DVT hastasının 24ünde D-dimer normalin üstünde ölçüldü. MDBT ile 10 hastaya PTE tanısı konuldu. Akut DVTye bağlı %40 oranında asemptomatik PTE geliştiği tespit edildi. Sonuç: Multi-detektor bilgisayarlı tomografi tanı değeri açısından V/P sintigrafisinden daha faydalı bulundu.
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    Effects of coronary revascularization and concomitant aneurysmectomy on QT interval duration and dispersion
    (Journal of Electrocardiology, 2006) Koşar, Feridun; Nisanoğlu, Vedat; Aksoy, Yüksel; Çolak, Mehmet Cengiz; Erdil, Nevzat; Battaloğlu, Bektaş
    A reduction in QT dispersion (QTd) has been previously shown in patients receiving thrombolytics and undergoing coronary artery bypass grafting (CABG). The purpose of the present study was to investigate changes occurring in corrected QT intervals or QT dispersion after CABG and concomitant aneurysmectomy in the same session. The study population included 43 patients with coronary artery disease with left ventricular aneurysm (LVA). The control group included 32 patients with coronary artery disease without LVA. The study patients underwent CABG and aneurysmectomy in the same surgical session. Corrected maximum and minimum QT interval duration (QTcmax and QTcmin) and corrected QT dispersion (QTcd) were measured in the study patients before and after surgery. QTcmax and QTcd in the patients with LVA were significantly higher than in the patients without LVA ( P b .001 and P b .001, respectively). QTcmax and QTcd in the patients with LVA were significantly shortened after surgery ( P b .001 and P b .001, respectively). This study showed that QTcmax and QTcd values are significantly reduced after CABG and concomitant aneurysmectomy. We have suggested that coronary revascularization and left ventricular reconstruction in the same session have beneficial effects on QT interval duration and dispersion.
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    Effects of electromagnetic radiation from 3G mobile phone on heart rate blood pressure and ECG parameters in rats
    (Toxicology and Industrial Health, 2012) Çolak, Mehmet Cengiz; Parlakpınar, Hakan; Ermiş, Necip; Çolak, Cemil; Sarıhan, Mehmet Ediz; Of, Dilek; Turan, Bahadır; Bakır, Sevtap; Acet, Hacı Ahmet
    Effects of electromagnetic energy radiated from mobile phones (MPs) on heart is one of the research interests. The current study was designed to investigate the effects of electromagnetic radiation (EMR) from thirdgeneration (3G) MP on the heart rate (HR), blood pressure (BP) and ECG parameters and also to investigate whether exogenous melatonin can exert any protective effect on these parameters. In this study 36 rats were randomized and evenly categorized into 4 groups: group 1 (3G-EMR exposed); group 2 (3G-EMR exposed þ melatonin); group 3 (control) and group 4 (control þ melatonin). The rats in groups 1 and 2 were exposed to 3G-specific MP’s EMR for 20 days (40 min/day; 20 min active (speech position) and 20 min passive (listening position)). Group 2 was also administered with melatonin for 20 days (5 mg/kg daily during the experimental period). ECG signals were recorded from cannulated carotid artery both before and after the experiment, and BP and HR were calculated on 1st, 3rd and 5th min of recordings. ECG signals were processed and statistically evaluated. In our experience, the obtained results did not show significant differences in the BP, HR and ECG parameters among the groups both before and after the experiment. Melatonin, also, did not exhibit any additional effects, neither beneficial nor hazardous, on the heart hemodynamics of rats. Therefore, the strategy (noncontact) of using a 3G MP could be the reason for ineffectiveness; and use of 3G MP, in this perspective, seems to be safer compared to the ones used in close contact with the head. However, further study is needed for standardization of such an assumption.
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    The effects of N acetylcysteine on pulmonary functions in patients undergoing on pump coronary artery surgery a double blind placebo controlled study
    (Eur rev med pharmacol sci, 2016) Erdil, Nevzat; Eroğlu, Tamer; Akça, Barış; Dişli, Olcay Murat; Yetkin, Özkan; Çolak, Mehmet Cengiz; Erdil, Feray Akgül; Battaloğlu, Bektaş
    Abstract. – OBJECTIVE: To investigate the effects of N-acetylcysteine (NAC) on pulmonary function tests and arterial blood gases in patients undergoing on-pump coronary artery surgery. PATIENTS AND METHODS: The effect of NAC was assessed within the scope of a prospective, single center, double-blind, placebo-controlled, parallel group study. Eighty-two patients undergoing coronary artery bypass grafting were randomized into two groups to receive either placebo (group 1, n = 40) or NAC (group 2, n=42). Both the NAC group and the placebo-receiving control group also included a COPD subgroup consisting of patients with an FEV1/FVC ratio of < 0.7 and an FEV1 value of 50- 80%. Pulmonary function tests were performed preoperatively and on postoperative day 60. RESULTS: Both groups were similar with respect to age, gender, preoperative risk factors, ejection fraction (EF), mean cross-clamp time, ventilation time, intensive care unit (ICU) stay, atrial fibrillation (AF) and hospital stay (p > 0.05). Postoperative FVC and FEV1 values in group 1 and the postoperative FEV1, FEV1/FVC and FEF 25-75 values in group 2 were lower in comparison to their preoperative values. However, in both group 1 and 2, the decreases observed in these parameters were not statistically significant (p > 0.05). In the COPD subgroup of group 1, a postoperative decrease was observed in the FEV1 and FEF25-75 values, with the FEV1 decreasing by 4.55%, and the FEF25-75 decreasing by 4.2% (p < 0.05). In the COPD subgroup of group 2, no significant decrease was observed in the pulmonary function test values (p > 0.05).
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    The effects of pulmonary hypertension on early outcomes in patients undergoing coronary artery bypass surgery
    (Turk J Med Sc, 2016) Akça, Barış; Dönmez, Köksal; Dişli, Olcay Murat; Erdil, Feray Akgül; Çolak, Mehmet Cengiz; Battaloğlu, Bektaş; Erdil, Nevzat
    Background/aim: To investigate the effects of pulmonary hypertension on early clinical variables in patients undergoing coronary artery bypass grafting surgery. Materials and methods: The preoperative echocardiographic data of patients who underwent isolated coronary artery bypass surgery were evaluated retrospectively. A total of 1244 patients were included in the study. The patients were divided into two groups: one group consisted of patients with systolic pulmonary artery pressure (SPAP) values equal to or greater than 30 mmHg (Group 1, n = 184), while the other group consisted of patients with SPAP values below 30 mmHg (Group 2, n = 1060). Results: Early mortality was similar in both groups (0% in Group 1 and 1.2% in Group 2; P > 0.05). Comparison of postoperative data indicated that Group 1 had a higher need for inotropic agent treatment, a longer average duration of ventilation, and a longer average duration of stay in the intensive care unit (P < 0.05). For the other variables, no significant differences were identified between patients with and without pulmonary hypertension (P > 0.05). Conclusion: Mild pulmonary hypertension (mean SPAP = 37.7 ± 8.4 mmHg) was not associated with a significant difference in the mortality of patients undergoing coronary artery bypass grafting. For patients undergoing this type of coronary bypass surgery, lower morbidity and mortality rates can be achieved through comprehensive preoperative examinations and effective perioperative medical procedures.
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    Effects of rivaroxaban on myocardial ischemia-reperfusion injury in rats
    (2022) Kahraman, Ercan; Akça, Barış; Çolak, Mehmet Cengiz; Disli, Olcay Murat; Parlakpınar, Hakan; Battaloglu, Bektas; Erdil, Nevzat
    Myocardial infarction and further ischemia-reperfusion injury is a life-threatening conditions in humans. In this study, the effects of rivaroxaban, an anticoagulant agent, were aimed to be studied in a myocardial ischemia-reperfusion (I/R) injury model in rats. Male Wistar-albino rats were allocated into three groups; Rivaroxaban (n=15), control (n=15) and sham (n=10). Myocardial ischemia (30 minutes) and then reperfusion (120 minutes) were surgically performed in the rivaroxaban given (3mg/kg/ day by gavage for 10 days before surgical procedures) and the control groups. Electrocardiography changes, blood pressure and heart rate were recorded before ischemia, and during the periods of ischemia and the reperfusion. Hemodynamic and blood parameters were recorded. Necrotic tissue in the myocardium was determined by the triphenyl tetrazolium chloride dye method. The extent of myocardial necrosis and risk area was calculated using a computer-assisted image program. In the rivaroxaban administered group, the size of necrotic area in the myocardium decreased significantly, however, mean heart rate and mean arterial blood pressure did not change. K+ and CK levels in serum, which are indicative of tissue necrosis, were significantly lower in the rivaroxaban group compared to the control group (p<0.05). Rivaroxaban use, compared to the control group, effectively reduced the extent of myocardial injury as assessed by less necrotic myocardial tissue in rats. This protective effect of rivaroxaban may be attributed to its less thrombus formation in the coronary arteries during ischemia and less acidosis during tissue damage.
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    Emergency surgical treatment of a percutaneous closure device complication in a patient with transfemoral transcatheter aortic valve implantation
    (2019) Erdil, Nevzat; Akça, Barış; Çolak, Mehmet Cengiz
    [Abstract Not Acailable]
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    he effects of pulmonary hypertension on early outcomes in patients undergoing coronary artery bypass surgery
    (Turkish Journal of Medical Sciences, 2016) Akça, Barış; Dönmez, Köksal; Dişli, Olcay Murat; Erdil, Feray Akgül; Çolak, Mehmet Cengiz; Aydemir, İlhan Koray; Battaloğlu, Bektaş; Erdil, Nevzat
    Öz (İngilizce): Background/aim: To investigate the effects of pulmonary hypertension on early clinical variables in patients undergoing coronary artery bypass grafting surgery. Materials and methods: The preoperative echocardiographic data of patients who underwent isolated coronary artery bypass surgery were evaluated retrospectively. A total of 1244 patients were included in the study. The patients were divided into two groups: one group consisted of patients with systolic pulmonary artery pressure (SPAP) values equal to or greater than 30 mmHg (Group 1, n = 184), while the other group consisted of patients with SPAP values below 30 mmHg (Group 2, n = 1060). Results: Early mortality was similar in both groups (0% in Group 1 and 1.2% in Group 2; P > 0.05). Comparison of postoperative data indicated that Group 1 had a higher need for inotropic agent treatment, a longer average duration of ventilation, and a longer average duration of stay in the intensive care unit (P < 0.05). For the other variables, no significant differences were identified between patients with and without pulmonary hypertension (P > 0.05). Conclusion: Mild pulmonary hypertension (mean SPAP = 37.7 ± 8.4 mmHg) was not associated with a significant difference in the mortality of patients undergoing coronary artery bypass grafting. For patients undergoing this type of coronary bypass surgery, lower morbidity and mortality rates can be achieved through comprehensive preoperative examinations and effective perioperative medical procedures.
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    Hemodializ amaçlı arteriyovenöz fistül sonrası gelişen rüptüre dev anevrizma
    (2014) Yılmaz, Mehmet; Dişli, Olcay Murat; Kahraman, Ercan; Akça, Barış; Dönmez, Köksal; Çolak, Mehmet Cengiz; Erdil, Nevzat; Battaloğlu, Bektaş
    Öz: Arteriyovenöz fistül (AVF) operasyonları, kronik böbrek yetmezliği olan olgularda hemodiyaliz uygulanmasını kolaylaştıran ve olgunun yaşam standartlarını yükseltmek amacıyla en sık kullanılan yöntemlerdir. Fistülün kullanılmasına bağlı geç dönemde en sık rastlanan komplikasyonlardan biri anevrizma gelişimidir. Bu çalışmada hemodiyaliz amaçlı açılan AVFnin, geç dönem komplikasyonu olarak ortaya çıkan rüptüre dev bir anevrizma olgusuna uyguladığımız cerrahi tedavi yaklaşımımız ve sonrasındaki klinik düzelmeyi özetlemeyi amaçladık.
  • Küçük Resim
    Öğe
    Intravascular branul fracture
    (Turgut Özal Tıp Merkezi Dergisi, 2016) Çolak, Mehmet Cengiz; Eser, Gökçe; Erdil, Nevzat; Akça, Barış; Erkul, Gözde; Battaloğlu, Bektaş
    Abstract The peripheral vascular catheter is usually used in intensive care patients to perform medical treatment and invasive blood pressure monitoring. However, during or after this procedure, some complications can develop. One of the complications is intravascular branule fractures. The delay of the treatment process can increase the incidence and severity of complications. Radiography and ultrasonography may be useful for early diagnosis. The reliability of ultrasonography in acute cases is quite high but it can be inadequate in delayed cases or when broken components have moved to a more proximal position. Besides these complications also cause legal actions taken against physicians and health care professionals. In this case, we aim to present the case of a branule fracture in which broken part of a branule remained within the vessel until our peripheral vascular intervention. Keyword: Peripheral Catheterization; Complications; Embolism.
  • Küçük Resim
    Öğe
    İntravasküler branül fraktürü
    (J Turgut Ozal Med Cent, 2016) Çolak, Mehmet Cengiz; Eser, Gökçe; Erdil, Nevzat; Akça, Barış; Erkul, Gözde; Battaloğlu, Bektaş
    The peripheral vascular catheter is usually used in intensive care patients to perform medical treatment and invasive blood pressure monitoring. However, during or after this procedure, some complications can develop. One of the complications is intravascular branule fractures. The delay of the treatment process can increase the incidence and severity of complications. Radiography and ultrasonography may be useful for early diagnosis. The reliability of ultrasonography in acute cases is quite high but it can be inadequate in delayed cases or when broken components have moved to a more proximal position. Besides these complications also cause legal actions taken against physicians and health care professionals. In this case, we aim to present the case of a branule fracture in which broken part of a branule remained within the vessel until our peripheral vascular intervention.