Yazar "Ünlü, Serkan" seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Cerebrospinal fluid dynamics in patients with multiple sclerosis: the role of phase-contrast mrı inthe differential diagnosis of active and chronic disease(Korean radıologıcal soc, 121-8 yangjae-dong, seocho-gu, seoul 137-130, south korea, 2018) Oner, Serkan; Kahraman, Ayşegül Sağır; Özcan, Cemal; Özdemir, Zeynep Maraş; Ünlü, Serkan; Kamisli, Özden; Oner, ZulalObjective: Multiple sclerosis (MS) is an inflammatory disease characterized by demyelinating plaques in the white matter. Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a new hypothesis for the etiopathogenesis of MS disease. MS-CCSVI includes a significant decrease of cerebrospinal fluid (CSF) flow through the cerebral aqueduct secondary to an impaired venous outflow from the central nervous system. This study aimed to determine whether CSF flow dynamics are affected in MS patients and the contributions to differential diagnosis in active and chronic disease using phase-contrast magnetic resonance imaging (PC-MRI). Materials and Methods: We studied 16 MS patients with chronic plaques (group 1), 16 MS patients with active plaques-enhanced on MRI (group 2), and 16 healthy controls (group 3). Quantitatively evaluation of the CSF flow was performed from the level of the cerebral aqueduct by PC-MRI. According to heart rates, 14-30 images were obtained in a cardiac cycle. Cardiac triggering was performed prospectively using finger plethysmography. Results: No statistically significant difference was found between the groups regarding average velocity, net forward volume and the average flow (p > 0.05). Compared with the controls, group 1 and group 2, showed a higher peak velocity (5.5 +/- 1.4, 4.9 +/- 1.0, and 4.3 +/- 1.3 cm/sec, respectively; p = 0.040), aqueductal area (5.0 +/- 1.3, 4.1 +/- 1.5, and 3.1 +/- 1.2 mm(2), respectively; p = 0.002), forward volume (0.039 +/- 0.016, 0.031 +/- 0.013, and 0.021 +/- 0.010 mL, respectively; p = 0.002) and reverse volume (0.027 +/- 0.016, 0.018 +/- 0.009, and 0.012 +/- 0.006 mL, respectively; p = 0.000). There were no statistical significance between the MS patients with chronic plaques and active plaques except for reverse volume. The MS patients with chronic plaques showed a significantly higher reverse volume (p = 0.000). Conclusion: This study indicated that CSF flow is affected in MS patients, contrary to the hypothesis that CCSVI-induced CSF flow decreases in MS patients. These findings may be explained by atrophy-dependent ventricular dilatation, which may occur at every stage of MS.Öğe Evaluation of aqueductal cerebrospinal fluid flow dynamics withphase contrast cine magnetic resonance imaging in normalpediatric cases(Clinical Imaging, 2016) Öztürk, Mehmet; Sığırcı, Ahmet; Ünlü, SerkanPurpose: This study aimed to determine differences according to age groups and gender in the parameters of aqueductal cerebrospinal fluid (CSF) flow in childhood using phase-contrast cine magnetic resonance imaging (MRI) method. Materials and methods: This prospective study included 47 boys and 36 girls for a total of 83 healthy children. The cases were divided into three groups depending on age as infants (1–12 months), children (12–120 months), and adolescents (120–204 months). To quantitatively evaluate CSF flow, images in the transverse plane were taken at the cerebral aqueduct level using the phase-contrast MR angiography technique in a 1.5-T MR unit. Peak and average velocity (cm/s), cranial direction, caudal direction and net volume (ml), and aqueduct area (mm2 ) were calculated. To assess differences between the groups, a one-way analysis of variance and least significant difference tests were used. Results: A statistically significant difference was determined between children and adolescents in peak velocity and caudal direction volume (P=.012 and P=.039, respectively) and between infants and children in cranial direction volume (P=.036). Peak velocity, cranial direction, and net volume were higher in boys (P=.050, P= .016, and P=.029, respectively). There were no differences by age and gender in the aqueduct area. Conclusion: In conclusion, this study determined the normal values for the CSF flow parameters of velocity, volume, and aqueduct area using phase-contrast MRI in healthy children. Velocity and volume parameters varied according to age and sex and were not affected in the aqueductal area.Öğe Nöroendoskopik Üçüncü Ventrikülostomi Operasyonu Geçirmiş Olan Bir Hastanın Faz Kontrast- Manyetik Rezonans Görüntüleme ile BOS Akımının Değerlendirilmesi(Causapedia, 2017) Ünlü, Serkan; Doğan, Metin; Kahraman, Ayşegül Sağır; Yıldırım, İsmail OkanÖz: Nöroendoskopik üçüncü ventrikülostomi, hidrosefalitedavisinde başarı ile kullanılan, morbiditesi düşük,başarı oranı yüksek bir tekniktir. Üçüncü ventrikültavanına açılan şantın fonksiyonel olup olmamasıtedavinin etkinliğini için önemlidir. Faz kontrast manyetik rezonans (FK-MRG) tekniği, beyin omuriliksıvısı (BOS) akımı ve BOS akım yolu hakkında invazivişleme gerek duymadan bilgiler vermektedir. Biz bu olgusunumu ile nöroendoskopik üçüncü ventrikülostomioperasyonu uygulanmış hastanın ventrikülostomioperasyonunun fonksiyonel olup olmadığını anlamaküzere FK-MRG yöntemi ile yapılan değerlendirmeyi vebulgularını sunmayı amaçladıkÖğe Pancreatic inflammatory myofibroblastic tumor presenting with extracolonic obstruction(2020) İflazoğlu, Nidal; Kaplan Kozan, Serpil; Biri, Tuğba; Gökçe, Hasan; Ünlü, Serkan; Doğan, Serhat; Gökçe, Oruç NumanAbstract: Inflammatory myofibroblastic tumor is a rare soft tissue tumor which can be detected in many parts of the body. Its etiology and clinical behavior are not fully understood, and its treatment is controversial. This study aimed to present the management of a pancreatic tail case presenting with extra-colonic obstruction findings. Unblock distal pancreatectomy + left surrenalectomy + left hemicolectomy + splenectomy operation was made with R0 resection principles. Although there are some medical treatments reported in children and unresectable tumors in the medical literature, complete surgical resection following oncological principles seems to be the most important and main treatment modality in the treatment of inflammatory myofibroblastic tumors. However, inflammatory myofibroblastic tumor has many aspects that are not yet clearly understood, and it is a disease being continuously researched