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    Effects of Home-Based Aerobic Exercise Training on Glycemic Control and Lipid Profiles in Patients with Prediabetes and Type 2 Diabetes: A Randomized Controlled Study
    (AVES, 2021) Özdemir F.; Kilcik M.H.; Evren B.; Şahin I.; Çolak C.
    Objective: Diabetes is an important health condition; in recent years, its prevalence has increased dramatically. This study aimed to evaluate the effects of home-based aerobic exercise training on glycemic control and lipid profiles in patients with prediabetes and type 2 diabetes. Material and Methods: This study included a total of 65 patients with ages between 38 and 66 years. The participants were divided into prediabetes exercise group (group I, n = 17), prediabetes control group (group II, n = 17), type 2 diabetes exercise group (group III, n = 17), and type 2 diabetes control group (group IV, n = 14). Home-based aerobic exercise training was suggested to all individuals in exercise groups (30 min, 60% of maximum heart rate [220 beats/min minus their age], 3 days per week) by a physiotherapist. Results: Among the patients, 61.5% were male and 38.5% were female. Participants’ sociodemographic characteristics, such as age, sex, and body mass index values, were similar (P > .05). After follow-up, the fasting plasma glucose (FPG) and high-density lipoprotein cholesterol (HDL_C) values were different in group I (P < .05). However, there were no differences in group II (P > .05). Hemoglobin A1c, HDL_C, FPG, and postprandial plasma glucose variables showed significant differences in group III (P < .05). There was a significant difference only in FPG levels in group IV (P < .05). Conclusion: Home-based exercise program is important for improving the patient’s self-control of diabetes. However, patients need physiotherapy counseling for sustainable home-based exercise training. © 2021 AVES. All Rights Reserved.
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    Trace element status (Se, Zn, Cu) in heart failure
    (2006) Koşar F.; Şahin I.; Taşkapan Ç.; Küçükbay Z.; Güllü H.; Taşkapan H.; Çehreli Ş.
    Objective: It has been speculated that trace elements may play a role in the pathogenesis of heart failure. In the present study, we aimed to assess serum concentrations of selenium (Se), zinc (Zn) and copper (Cu) in patients with heart failure (HF) and to compare idiopathic dilated cardiomyopathy (IDCM) and ischemic cardiomyopathy (ICM) patients with healthy controls. Methods: This study population included 54 HF patients (26 IDCM patients and 28 ICM patients) and 30 healthy subjects. Serum levels of selenium, zinc, and copper were assessed by atomic absorption spectrophotometry method. Results: Serum concentrations of Se and Zn in HF patients were significantly lower than in healthy controls (p=0.000 and p<0.01, respectively). However, serum Cu concentrations in these patients were significantly higher than in controls (p=0.000). There were no significant difference in the trace elements status between IDCM and ICM patients (p>0.05 for all parameters). Relationships of the serum trace element concentrations studied with echocardiographic and hemodynamic parameters were not statistically significant. Conclusion: Our study showed that heart failure is associated with lower Se and Zn concentrations, and higher Cu concentration, and serum Se, Zn and Cu element profiles were similar in IDCM and ICM.