Yazar "Acar, Aylin" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim
    Öğe
    Gastrointestinal stromal tumors: Factors affecting prognosis and single-center surgery results
    (2019) Gundogan, Ersin; Gundogan Alinak, Gokcen; Kement, Metin; Cetin, Kenan; Acar, Aylin; Bildik, Nejdet
    Aim: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. The aim of this study was to investigate the clinical features and histopathological findings of GIST cases who underwent surgical treatment in our clinic in terms of prognostic criteria. Material and Methods: The patients operated for GIST between January 1, 2007 and May 31, 2014 were included in this study. Demographic data, presenting symptoms, ASA scores, diagnostic methods, tumor localizations, use of imatinib before surgery, surgical treatment methods, postoperative complications, tumor size, mitotic activity, immunohistochemical markers, prognostic risk classification, follow-up periods, use of imatinib after surgery, recurrence status and survival data were examined Results: A total of 60 patients were included in the study. The median age was 56.5 (29-81) years . Fifty five of patients were males. Synchronous tumors in more than one location existed in approximately 7% of the patients. The surgical margin was positive in 14 (23.3%) patients after the surgical procedure. The recurrence and metastasis rates of these patients were 14.3% and 42.8%, respectively. On the other hand, these rates were 10.8% and 17.3% respectively in the patients with negative surgical margin. The expected 5-year survival rates according to the risk classification was 66.7% for very low-risk patients, 85.7% for low-risk patients, 59.7% for moderate-risk patients and 47.7% for high-risk patients. Conclusion: GISTs have relatively good prognosis compared to epithelial malignant tumors but require long-term follow-up. In addition, satisfactory results can be obtained with the use of tyrosine kinase inhibitors and adequate surgical margins
  • Küçük Resim
    Öğe
    Gastrointestinal stromal tumors: Factors affecting prognosis and single-center surgery results
    (2019) Gündoğan, Ersin; Alınak Gündoğan, Gökçen; Kement, Metin; Çetin, Kenan; Acar, Aylin; Bildik, Nejdet
    Abstract: Aim: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. The aim of this study was to investigate the clinical features and histopathological findings of GIST cases who underwent surgical treatment in our clinic in terms of prognostic criteria. Material and Methods: The patients operated for GIST between January 1, 2007 and May 31, 2014 were included in this study. Demographic data, presenting symptoms, ASA scores, diagnostic methods, tumor localizations, use of imatinib before surgery, surgical treatment methods, postoperative complications, tumor size, mitotic activity, immunohistochemical markers, prognostic risk classification, follow-up periods, use of imatinib after surgery, recurrence status and survival data were examined Results: A total of 60 patients were included in the study. The median age was 56.5 (29-81) years . Fifty five of patients were males. Synchronous tumors in more than one location existed in approximately 7% of the patients. The surgical margin was positive in 14 (23.3%) patients after the surgical procedure. The recurrence and metastasis rates of these patients were 14.3% and 42.8%, respectively. On the other hand, these rates were 10.8% and 17.3% respectively in the patients with negative surgical margin. The expected 5-year survival rates according to the risk classification was 66.7% for very low-risk patients, 85.7% for low-risk patients, 59.7% for moderate-risk patients and 47.7% for high-risk patients. Conclusion: GISTs have relatively good prognosis compared to epithelial malignant tumors but require long-term follow-up. In addition, satisfactory results can be obtained with the use of tyrosine kinase inhibitors and adequate surgical margins.
  • Küçük Resim
    Öğe
    Timing of cholecystectomy in the treatment of mild acute biliary pancreatitis
    (2020) Acar, Aylin; Canbak, Tolga; Tolan, Huseyin Kerem
    Aim: In this study, we aimed to compare the results of emergency and elective cholecystectomy in patients admitted due to acute biliary pancreatitis.Material and Methods: A total of 632 patients admitted due to acute biliary pancreatitis were retrospectively evalauted. Patients with Ranson ≥ 3 and hour 48 CRP > 15 were considered as severe pancreatitis and excluded from the study. Patients were divided into two groups. Group 1 consisted of the patients who underwent emergency cholecystectomy after 48 hours, while Group 2 included the patients who underwent interval cholecystectomy. Results: A total of 386 patients were enrolled in the study. Group 1 consisted of 214 patients. The mean Ranson score was found as 1.3±0.9 in Group 1 and 0.92±0.7 in Group 2. A total of 148 patients in Group 1 and 117 patients in Group 2 had comorbidity (p=0.81). Conversion was performed in 8 patients in Group 1 and 5 patients in Group 2 (p = 0.78). Bile duct injury was not detected in either group. Among the patients in the interval cholecystectomy group, 7 patients were admitted to the hospital due to acute pancreatitits and total 13 patients due to biliopancreatic reasons during the interval period. Conclusion: No effect of cholecystectomy timing was detected on the conversion rates and development of complications. However, development of recurrence and related complications in the waiting period of the patients could be prevented by performing early cholecystectomy.