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    Clinical and Histopathological Analysis of Premalignant and Malignant Lesions of Eyes and Adnexes Diagnosed in Our Clinic
    (Inonu University, 2023) Dikci, Seyhan; Akatli, Ayşe Nur
    Our aim is to perform clinicopathological analysis of premalignant and malignant lesions of the eye and adnexa diagnosed in a tertiary clinic. The files of the patients who underwent surgery and sent specimens to pathology laboratory at Inönü University Faculty of Medicine, Department of Ophthalmology between March 2010 and July 2020 were reviewed retrospectively. Demographic, clinical and histopathological data of cases with premalignant and malignant lesions were recorded. A total of 136 patients, 64 (47.1%) female and 72 (52.9%) male, were included in the study. The mean age of the patients was 73.6±14.7 (11-101) years. Premalignant lesions were detected in 58 patients (42.6%) and malignant lesions were detected in 78 patients (57.4%). The most common premalignant lesions were conjunctival or corneal intraepithelial neoplasia, carcinoma in situ, while the most common malignant lesions were basal cell carcinoma, squamous cell carcinoma, and lymphoma. In our clinic, the most commonly diagnosed premalignant lesion of the eyes and adnexa was conjunctival intraepithelial neoplasia, and the malignant lesion was basal cell carcinoma. © 2023, Inonu University. All rights reserved.
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    Concurrence of polyostotic fibrous dysplasia and spinal aspergillus in non-immunocompromised adult patient: Case report
    (Inonu University Faculty of Medicine Department of Neurosurgery, Malatya, Turkey, 2017) Pasahan, Ramazan; Durak, Mehmet Akif; Aladag, Mehmet Arif; Akatli, Ayşe Nur; Yildirim, Ismail Okan
    Öz: Aspergillus, a rare agent in spinal infections, is often transmitted via inhalation. It can be traced as an infectious agent in immuno- compromised patients. While in non-immunocompromised patients, it is highly unlikely to cause spondylodiscitis. Radiological find- ings remind tuberculosis. The recommended medical treatment is applied with Itraconazole and Amphotericin B. Surgical indication involves the presence of progressive neurological deficit, instability and biopsy requirement. Fibrous dysplasia was first reported in 1938 by Lichtenstein and is a benign developmental disorder of the skeletal system with uncertain etiology. Polyostotic type involved more than one bone, while the monostotic type occurs by involving only one bone structure. Spinal involvement may lead to collapse fractures and deformity development and the most common complaint is pain. In our case, these two disorders occur concurrently, causing bone destruction and severe pain, and no similar cases were found in the literature.
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    Concurrence of polyostotic fibrous dysplasia and spinal aspergillus in non-immunocompromised adult patient:case report
    (2017) Pasahan, Ramazan; Durak, Mehmet Akif; Aladag, Mehmet Arif; Akatli, Ayşe Nur; Yildirim, Ismail Okan
    Aspergillus, a rare agent in spinal infections, is often transmitted via inhalation. It can be traced as an infectious agent in immunocompromised patients. While in non-immunocompromised patients, it is highly unlikely to cause spondylodiscitis. Radiological findings remind tuberculosis. The recommended medical treatment is applied with Itraconazole and Amphotericin B. Surgical indication involves the presence of progressive neurological deficit, instability and biopsy requirement. Fibrous dysplasia was first reported in 1938 by Lichtenstein and is a benign developmental disorder of the skeletal system with uncertain etiology. Polyostotic type involved more than one bone, while the monostotic type occurs by involving only one bone structure. Spinal involvement may lead to collapse fractures and deformity development and the most common complaint is pain. In our case, these two disorders occur concurrently, causing bone destruction and severe pain, and no similar cases were found in the literature.
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    Eosinophilic ascites, as a rare manifestation of eosinophilic gastroenteritis: A case report
    (2018) Cagin, Yasir Furkan; Berber, İlhami; Bilgic, Yilmaz; Erdogan, Mehmet Ali; Yildirim, Oguzhan; Altunel Kilinc, Elif; Seckin, Yuksel; Akatli, Ayşe Nur
    Eosinophilic ascites (EA) can present as an unusual finding of eosinophilic gastroenteritis. We presented this case to remind eosinophilic acid in cases with unexplained etiology. A 29-years old man presented to an emergency department with abdominal swelling, progressively worsening nausea, and fatigue over one month. The patient had no history of allergic disease. There was moderate ascites in the physical examination. Percent eosinophil was 60% in peripheral blood smear while IgE level was increased in the serum. There was ascites on abdominal computed tomography (CT) scan. Serum ascites-albumin gradient (SAAG) was non-portal. Eosinophilic infiltration was detected biopsy samples obtained by upper GI tract endoscopy and in bone marrow aspiration and biopsy. The abdominal pain, ascites and all laboratory tests were completely recovered after 12 weeks of prednisolone therapy. Eosinophilic gastroenteritis should be considered in case of markedly increased eosinophilia in ascites fluid.