Yazar "Aktas, A." seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Colonic fibronectin and E-cadherin in mild ulcerative colitis(Comenius Univ, 2021) Sarpdag, F.; Yonem, O.; Aktas, A.; Seckin, Y.; Tuncer, E.; Ozer, H.BACKGROUND: Although fibronectin has an important role in wound repair, nearly no human studies to date have investigated its condition in ulcerative colitis (UC) histologically. E-cadherin plays a critical role in the repair of normal epithelial tissues. This study aims to find out the condition of these two molecules in UC. MATERIAL AND METHODS: The records of 22 UC patients during the period of 2004-2009 were retrospectively analyzed. We also included 24 patients with sporadic colorectal cancer (SCC) and 24 patients with normal colonoscopic biopsies who served as the control group. Colonoscopic biopsies were stained with E-cadherin and fibronectin. RESULTS: The E-cadherin loss was significantly more prominent in the SCC group, followed by the UC group and control group. The situation was reverse for fibronectin. We also observed that while the E-cadherin loss was still ongoing in all of the endoscopically inactive cases, the fibronectin staining resembled the staining pattern of normal individuals in ten out of thirteen UC patients. CONCLUSION: We suggest that the decrease in E-cadherin, even in the inactive period, might be the cause of why UC is not just a compensatory change in repair of inflammation. The results of staining with fibronectin in UC patients were between normal individuals and SCC patients. Further studies are necessary to confirm our results (Tab. 2, Fig. 6, Ref. 15).Öğe The Effect of Dietary Supplements on Healing of Alloplastic Bone Grafted Defects in Rat Tibia(Soc Chilena Anatomia, 2015) Kaya, A.; Aktas, A.; Akdemir, M. F.; Kaya, B.; Deveci, E.The aim of this investigation was to evaluate the potential effects of the systemically delivered combination of calcium, zinc and vit-d supplementation of the locally applied alloplastic bone graft. 28 male Wistar albino rats were used in this study. In each animal, bone defects (10 mm length (sic) 3 mm width (sic) 2 mm depth) were created in the tibias. The animals were divided into four groups. In Group 1 (Control Group) rats were fed with standard rat diet. In Group 2 (Calcium Group) rats received calcium carbonate (15 mg/kg body weight) suspended in saline. In Group 3 (Calcium/Zinc Group) rats received calcium carbonate (15 mg/kg body weight) and zinc sulfate (4 mg/kg body weight) suspended in saline. In Group 4 (Calcium/Vitamin D Group) rats received calcium carbonate (15 mg/kg body weight) and Vitamin D (500 IU/kg body weight) suspended in olive oil. Histopathological analysis of samples was performed to evaluate the process of osteoblastic activity, matrix formation, trabecular bone formation and myeloid tissue in bone defects. Total amounts of osteoblastic activity, matrix formation, trabecular bone formation and myeloid tissue in Ca Group (p= 0.002), Ca/Zinc Group (p= 0.002), and Ca/Vit.D Group (p= 0.001) were significantly higher than in Control Group. The total amounts of Ca/Vit.D Group were significantly different than Control Group and Ca Group. The results of the present study indicated that the oral calcium carbonate supplementation combination with zinc may have systemic effects on accelerating bone regeneration in alloplastic bone grafted tibial defects. Further human studies involving long-term follow up and different type of bone grafts should be conducted.Öğe Laparoscopic management of bowel obstruction due to multiple congenital adhesion bands in pregnancy - a video vignette(Wiley, 2018) Bengur, F. B.; Bas, M.; Aktas, A.; Yozgatli, T. K.; Bilgin, I. A.; Ozben, V.; Aytac, E.[Abstract Not Available]Öğe Laparoscopic management of bowel obstruction due to multiple congenital adhesion bands in pregnancy - a video vignette(Colorectal dısease, 2018) Bengur, F. B; Bas, M.; Aktas, A.; Yozgatli, T. K; Bilgin, I. A; Ozben, V.; Aytac, E.; Baca, B; Hamzaoglu, I.; Karahasanoglu, T.
