Yazar "Akyoldas, Goktug" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    The investigation of vasospastic effect of hemostatic matrix used in intracranial operations on cerebral arteries
    (2019) Kalemci, Orhan; Akyoldas, Goktug; Ersen Danyeli, Ayca; Acis, Onur; Kizmazoglu, Ceren; Ur, Koray; Arda, Mehmet Nuri
    Aim: We aimed to investigate the vasospastic effect of thrombin-based hemostatic matrix on the basilar arteries in rats.Material and Methods: A total of 28 female albino Wistar rats were used in the study. The rats were randomly assigned to four groups. The rats in group I (control group) were sacrificed without surgical manipulation. We injected 0.1 mL of nonheparinized autologous arterial blood into the cisterna magna of the rats in group II, 0.1 mL of hemostatic matrix into the cisterna magna of the rats in group III, and 0.1 mL of a mixture of nonheparinized autologous arterial blood and the hemostatic matrix into the cisterna magna of the rats in group IV. The experimental rats were sacrificed 48 hours after injections. Three sections were obtained from each rat’s basilar arteries and photographed under a light microscope. Basilar artery cross-section areas were measured using computerized image analysis systems.Results: Mean basilar artery cross-sections of all groups revealed statistically a significant difference between only group I and group II. The mean basilar artery cross-sec-tion areas of groups II, III, and IV decreased by 36%, 19%, and 22%, respectively, in comparison with those of group I.Conclusion: Although our results pertaining to thrombin-based hemostatic matrix were not statistically significant, it is hypothesized that this matrix has a vasospastic effect on arteries. Therefore, it important to remember that when such a matrix is used in cranial surgery, the thrombin contained therein could have a vasospastic effect on cerebral arteries.Keywords: Cerebral vasospasm; hemostatic matrix; thrombin; rat; subarachnoid hemorrhage.
  • Küçük Resim
    Öğe
    Short-segment pedicle screw-based semi-rigid stabilization with poly (etheretherketone) rods for treatment of degenerative lumbar scoliosis in elderly patients
    (2020) Akyoldas, Goktug
    Aim: This study analyzed outcomes after short-segment pedicle screw-based semi-rigid stabilization with Poly (etheretherketone) (PEEK-polymer) rods in elderly patients with degenerative lumbar scoliosis. To date, there is no high level of evidence (Level-I) in the relevant literature. Therefore, this is the initial report about use of PEEK-polymer rods in elderly patients with degenerative lumbar scoliosis.Material and Methods: From January 2015 to June 2017, 31 patients aged over 60 years with degenerative lumbar scoliosis, who underwent pedicle screw-based semi-rigid stabilization with PEEK-polymer rods were investigated. All medical records and radiological images were reviewed to evaluate surgery-related complications and clinical outcomes.Results: Patients demonstrated clinically significant functional improvement (Oswestry Disability Index) with an average of 69.3% during an average follow-up of 36.1 months (range, 24–54 months) after surgery. Patients displayed significant Visual Analog Scale (VAS) improvements when comparing pre- and postoperative scores at an average change of 76% and 80% for VAS for back pain and leg pain, respectively. No neurological deficit was observed after surgery.Conclusion: Satisfactory percentage in functional and pain improvement as well as low rate of instrument-related complications was obtained after pedicle screw-based stabilization with PEEK-polymer rods. This system can now be considered a viable option in elderly patients with the degenerative lumbar scoliosis.